Publications by authors named "Toshiyuki Komaki"

A 72-year-old man had been undergoing chemotherapy for advanced gastric cancer for over 4 years. He presented with dysphagia, and esophagogastroduodenoscopy(EGD)revealed esophageal stricture due to tumor growth. Subsequently, he underwent placement of a partially covered esophageal stent(HANAROSTENT® Esophagus, M.

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A 67-year-old woman presented with a history of upper abdominal pain and weight loss. Physical examination revealed a lump in the right lower quadrant. She had undergone esophagogastroduodenoscopy at another hospital ten years ago, which showed a 15-mm elevated lesion in the duodenal bulb.

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Bleeding frequently occurs during gastric endoscopic submucosal dissection (ESD) and bleeding points are sometimes difficult to detect. Red dichromatic imaging (RDI) was recently developed to improve the visibility of bleeding. Our study aimed at examining the efficacy of RDI in improving the visibility of bleeding during gastric ESD.

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Purpose: Anamorelin, a ghrelin receptor agonist, has recently been approved for gastric, pancreatic, and colorectal cancer patients with cachexia in Japan. However, only few studies have investigated the predictors of response to anamorelin in clinical settings. Thus, our study aimed to investigate the predictors of the response, in addition to its efficacy and safety.

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Article Synopsis
  • Endoscopic retrograde cholangiopancreatography (ERCP) is a common medical procedure but can lead to a serious complication called post-ERCP pancreatitis (PEP), which researchers are trying to prevent.
  • This study investigated whether low doses of rectal diclofenac (an anti-inflammatory drug) could effectively prevent PEP by comparing outcomes between patients who received the drug and those who didn't.
  • Results showed no significant difference in the incidence or severity of PEP between the group receiving diclofenac and the control group, indicating that low-dose diclofenac is not effective in reducing PEP risks.
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  • A sixty-year-old male with advanced pancreatic ductal adenocarcinoma (PDAC) was treated with gemcitabine and nab-paclitaxel, leading to complications including nonspecific interstitial pneumonitis but no signs of infection.
  • After further investigation, it was discovered the patient had been taking a dietary supplement, Murill extract, which might have contributed to his lung issues.
  • The patient's condition improved after stopping the supplement, highlighting the importance of thorough patient interviews for diagnosing drug-induced interstitial lung disease (ILD).
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To evaluate the volume and heat-sink effects of microwave ablation (MWA) in the ablation zone of the normal swine lung. MWA at 100 W was performed for 1, 2, and 3 min in 7, 5, and 5 lung zones, respectively. We assessed the histopathology in the ablation zones and other outcome measures: namely, length of the longest long and short axes, sphericity, ellipsoid area, and ellipsoid volume.

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  • The study analyzed the bacterial spectrum in patients experiencing first and second episodes of acute cholangitis, highlighting the need for appropriate antibiotic treatment based on the episode.
  • In the first episode, common strains were primarily Escherichia coli and Klebsiella spp., while Enterococcus spp. dominated in recurrent episodes.
  • It suggests that medical professionals should use anti-enterococcal antibiotics for patients with repeated cases of acute cholangitis, contrasting the treatment for first episodes.
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The impact of the psoas muscle mass index (PMI) on survival is still poorly understood in unresectable pancreatic cancer. Thus, we aimed to investigate whether the PMI at diagnosis or its decrease during chemotherapy can influence the prognosis of unresectable pancreatic cancer. The data of 100 patients were analyzed, and they were divided into two groups according to the median PMI in each sex.

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Purpose: We summarized the findings, diagnosis, and outcomes of cases for which contrast examination of central venous access ports (CV-ports) were attempted to detect complications.

Materials And Methods: Fifty-seven contrast examinations were attempted for 45 patients with 46 CV-ports (median, 162 days after implantation). Contrast examination was performed due to three suspicion catheter fractures or 54 CV-port dysfunctions (combinations of an absence of blood reflux on aspiration and 9 sufficient, 21 insufficient, or 24 impossible drip infusions).

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Article Synopsis
  • - Colon cancer featuring mucinous components can lead to complications such as bacterial infections.
  • - These infections can result in the formation of abscesses, which are pockets of pus in the body.
  • - The presence of both cancer and infection highlights the complexity of treating such cases in medical settings.
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Small renal tumors are sometimes challenging to diagnose accurately through imaging alone, and image-guided biopsies are performed when histological diagnoses are needed. Although ultrasound guidance is usually chosen for renal tumor biopsies, computed tomography guidance is preferred for selected cases; e.g.

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To assess the feasibility of needle tract ablation in liver tissue in ex vivo and in vivo animal models using a cryo-probe and electrosurgical device. The experimental device is made by inserting a cryoprobe through an intro-ducer sheath for insulation, with 2-cm of probe tip projecting out. A beagle liver was punctured by the device, and electric current was applied at 30-W with the electrosurgical knife touching the non-insulated device base.

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Background: We frequently encounter early gastric cancer (EGC) that could not be detected in the previous esophagogastroduodenoscopy even if the procedure was annually performed. However, little evidence exists regarding the characteristics of false-negative EGCs. Our aim was to reveal the clinical features of false-negative EGCs.

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A 49-year-old man underwent treatment with glecaprevir plus pibrentasvir (G/P) for chronic hepatitis C infection. Six weeks later, he was admitted to our hospital because of jaundice and fatigue with no accompanying skin rash. A laboratory examination and evaluation of the patient's history resulted in a diagnosis of acute liver injury.

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Purpose: To evaluate the characteristics of needle artifacts and the accuracy of needle insertion using a 1.2 Tesla open magnetic resonance imaging (MRI) system in a phantom.

Materials And Methods: First, the apparent width of the needle on the MRI and the needle tip position error of 16- and 18-gauge MRI-compatible introducer needles and a 17-gauge cryoneedle were examined with different needle angles (0°, 30°, 45°, 60°, and 90°) to the main magnetic field (B0), sequence types (balanced steady-state acquisition with rewound gradient echo [BASG] and T2-weighted fast spin echo [FSE] sequence), and frequency encoding directions.

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Background: Percutaneous cryoablation is widely used for the treatment of renal cell carcinoma. We prospectively evaluated the oncologic outcomes and safety of percutaneous cryoablation for the treatment of tumors ≤ 4 cm in diameter.

Methods: We included patients aged ≥ 20 years, who had histologically proven renal cell carcinoma, tumor diameter ≤ 4 cm, a performance status of ≤ 1, acceptable laboratory parameters, were inoperable or refused to undergo surgery, and had signed a written informed consent.

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Inflammation-based prognostic indicators have been developed to predict the prognosis in patients with pancreatic cancer. However, prognostic indices have not been established in patients with unresectable pancreatic cancer, including those without indication for chemotherapy at diagnosis. This study aimed to identify the predictors in all patients with unresectable pancreatic cancer.

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A 77-year-old man with chronic hepatitis C (CH-C) infection, who achieved a sustained virological response (SVR) to interferon (IFN) therapy, was followed up regularly. Before IFN therapy, he did not have metabolic diseases, and the histological diagnosis of his chronic hepatitis was stage-3 fibrosis. After achieving SVR, the fibrosis-4 (FIB-4) index level dropped once but gradually increased.

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We report a 47-year-old Japanese female with 10 previous treatments for multiple bilateral renal cell carcinoma (RCC) associated with von Hippel-Lindau disease. The 14-mm right lower pole renal tumor was in contact with the right ureter. Laparoscopic cryoablation was performed to protect the ureter wrapped with gauze.

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A 70-year-old male was diagnosed with tiny capillary hemangioma of the ileum using double-balloon endoscopy. Capillary hemangiomas should be included in the differential diagnoses of OGIB.

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A 54-year-old woman underwent chemotherapy including rituximab and autologous peripheral blood stem cell transplantation (auto-PBSCT) for diffuse large B-cell lymphoma. Before the treatment, she exhibited a resolved hepatitis B virus (HBV) infection. She was diagnosed with HBV reactivation based on positive serum HBV-DNA test results, 55 months after her last treatment.

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Signet-ring cell carcinoma, a colorectal cancer (CRC) subtype, sometimes shows metastases to uncommon metastatic sites. However, gastric metastasis is extremely rare. Here, we describe a case of gastric metastasis from colonic cancer.

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Purpose: To retrospectively evaluate the diagnostic yield and safety of computed tomography (CT) fluoroscopy-guided biopsy of abdominal para-aortic lesions.

Material And Methods: CT fluoroscopy-guided biopsy was performed for 30 lesions (median long diameter 2.4 cm; range, 1.

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A 69-year-old Japanese man underwent an endoscopic submucosal dissection (ESD) for early gastric cancer 2 years prior to admission at Fukuchiyama City Hospital. A follow-up esophagogastroduodenoscopy (EGD) revealed a butterfly-shaped brownish area in the cervical esophagus. A successful endoscopic submucosal dissection of the esophageal lesion was performed for total biopsy.

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