Publications by authors named "Toshiyuki Endo"
Introduction: Whether white blood cell (WBC) counts are predictors for the effectiveness of thiopurine treatment in ulcerative colitis (UC) has been inconclusive in previous studies with small sample sizes. We investigated the association between WBC counts and future relapses in UC patients in a large-scale multi-center study.
Methods: This retrospective cohort study enrolled a total of 723 UC patients in remission from 33 hospitals and followed up for 3 years.
Objectives: Acute hemorrhagic rectal ulcer syndrome (AHRUS) causes massive bleeding and often recurrent rebleeding from rectal ulcers that form immediately above the dentate line. This study aimed to determine the clinical background and risk factors contributing to rebleeding in patients with AHRUS and the most appropriate method of hemostasis treatment.
Methods: This retrospective study included 93 patients diagnosed with AHRUS at Showa University Fujigaoka Hospital, Japan, between April 2009 and November 2018.
Article Synopsis
- Sessile serrated lesions (SSL) are important precursors to colorectal cancers, and appropriate treatment, like endoscopic submucosal dissection (ESD), could help prevent these cancers.
- In a study involving 370 ESD cases, characteristics of SSL were compared to non-SSL, revealing trends like younger women and proximal colon locations being more common in the SSL group.
- The study found that ESD was safe and had better dissection speeds for SSL compared to non-SSL, suggesting ESD could be a viable treatment option for SSL.
Background And Aim: Cases of colorectal endoscopic submucosal dissection (ESD) with poor maneuverability are often encountered. We aimed to evaluate the efficacy of balloon-assisted endoscopy (BAE) for such cases.
Methods: We confirmed maneuverability preoperatively in 400 consecutive cases of colorectal ESD performed at a single center from April 2011 to April 2018.
Emphysematous gastritis is an extremely rare disease with an unfavorable prognosis. To date, very few studies have been conducted regarding the intragastric recovery process based on endoscopic findings. We herein report a case of emphysematous gastritis that improved with long-term (five months) conservative treatment in which we were able to observe the intragastric recovery process endoscopically.
View Article and Find Full Text PDFArticle Synopsis
- Small intestinal anisakiasis is a rare and challenging disease to diagnose, often requiring surgical intervention initially, but usually resolves with conservative treatment.
- A 63-year-old man with acute abdominal pain, following raw fish consumption, was diagnosed with small intestinal obstruction likely caused by anisakiasis through CT scans and antibody testing.
- The patient was successfully treated with conservative methods (fasting, fluid replacement, and an ileus tube), leading to symptom resolution and discharge within a week, highlighting that unnecessary surgery can often be avoided.
Five ethyl (5-alkyl-2-amino-1,3-thiazol-4-yl) acetates (designated compounds 4a-e) incorporating octyl, decyl, dodecyl, tetradecyl, and hexadecyl alkyl chains, respectively, were prepared by reacting 4-alkyl-4-bromo-3-oxobutyric acid ethyl esters (3a-e) with thiourea in dried acetonitrile. Compounds 3a-e were synthesized by reacting alkylated ethyl acetoacetates with bromine. The newly synthesized compounds were characterized by mass spectrometry, NMR, and elemental analysis.
View Article and Find Full Text PDF