Publications by authors named "Toshiro Honda"
Article Synopsis
- Lyme disease is caused by Borrelia spp., which are transmitted by Ixodes ticks, with recent discoveries of related species in Asia, specifically Borrelia valaisiana-related strains.
- A study identified and analyzed 19 strains of these Borrelia from mammals and ticks, showing significant genetic differences from their European counterparts and a connection to B. yangtze in China.
- The research suggests that small mammals and Ixodes granulatus ticks may act as reservoir hosts and vectors for this Borrelia species in Asia, in contrast to the European strains, which are primarily associated with birds and I. ricinus ticks.
Estimation of beta-cell function from the data of the oral glucose tolerance test.
Am J Physiol Endocrinol Metab
June 2007
Although a hyperbolic relationship between insulin secretion and insulin sensitivity has been shown, the relationship has been often questioned. We examined the relationship using oral glucose tolerance test (OGTT)-derived indexes. A total of 374 Japanese subjects who had never been given a diagnosis of diabetes underwent a 75-g OGTT.
View Article and Find Full Text PDFProtein tyrosine phosphatases (PTPases) play an essential role in the regulation of steady-state phosphorylation of the insulin receptor and other proteins in the insulin signaling pathway. To determine the role of PTPases in adipose tissue in the development into an insulin-resistant state, we examined PTPase activities and protein levels of three major candidate PTPases in adipose tissues of 26-week-old male Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Particulate PTPase activities in visceral and epididymal adipose tissues of OLETF rats were increased compared to those in Long-Evans Tokushima Otsuka (LETO) rats, non-insulin-resistant controls.
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