Genetic basis of hypertension for the development of tailored medicine.

Similar to a tsunami wave, a new surge of genome-wide association studies in common complex diseases has succeeded in identifying the causative genetic risk factors of hypertension. The current status of genomic studies in hypertension, however, remains disorganized, and there are no clear solutions in sight. One possible reason for this disorganization is the small effect of each genetic variant on the predisposition to hypertension.