Publications by authors named "Toshimitsu Yasui"
A woman in her 60s with cirrhosis and hepatitis C virus with sustained virologic response underwent multiple local treatments for hepatocellular carcinoma (HCC) starting in April 20xx. Computed tomography in December 20xx+6 revealed HCC recurrence and mass in left kidney. Pathologic evaluation after partial nephrectomy led to the diagnosis of renal metastasis of HCC, and treatment with atezolizumab and bevacizumab was initiated.
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- Zinc's role in hepatocellular carcinoma was investigated, focusing on the expression of zinc transporter 1 (ZNT1) and its correlation to clinical outcomes in patients who had surgery for the cancer.
- The study analyzed 65 patient cases between 2011 and 2015, measuring ZNT1 expression intensity through immunohistochemistry and assessing its relationship with various clinical parameters using statistical tests.
- Results showed that ZNT1 expression was linked to lower blood zinc levels and shorter overall survival, highlighting ZNT1 as a potential prognostic factor alongside tumor size in hepatocellular carcinoma patients.