Publications by authors named "Toshimasa Higuchi"
Article Synopsis
- Casein hydrolysate made from Aspergillus oryzae protease contains peptides that can lower blood pressure.
- A study with 144 subjects showed that those taking casein hydrolysate had significant reductions in both systolic and diastolic blood pressure after 12 weeks compared to a placebo group.
- The treatment was effective for individuals with both high-normal blood pressure and mild hypertension, with no reported side effects.
We characterized a gene cluster in a plasmid designated pPI-1 of Staphylococcus warneri ISK-1 encoding the biosynthesis of and immunity to the lacticin-481 type lantibiotic, nukacin ISK-1. The DNA sequence suggested that the nukacin ISK-1 gene cluster consists of at least six genes, nukA (a structural gene), -M, -T, -F, -E, -G, and two open reading frames, ORF1 and ORF7. NukM and NukT were predicted to be involved in post-translational modification and secretion of nukacin ISK-1 respectively.
View Article and Find Full Text PDF