Bilirubin and its oxidative metabolite biopyrrins in patients with acute myocardial infarction.

This study aimed to assess the involvement of bilirubin and its oxidative metabolite biopyrrin in patients with acute myocardial infarction (AMI) and to determine the responsible organs that overproduce these molecules. One hundred thirteen consecutive patients hospitalized for AMI were analyzed. Levels of serum bilirubin, plasma and urinary biopyrrins were measured on the day of admission, day 2, 3, 7 and 14.

High serum erythropoietin level is associated with smaller infarct size in patients with acute myocardial infarction who undergo successful primary percutaneous coronary intervention.

Objectives: We investigated whether a higher serum erythropoietin (EPO) level in patients with acute myocardial infarction (MI) subjected to successful primary percutaneous coronary intervention (PCI) can predict a smaller infarct size determined by creatine kinase (CK) release.

Background: Erythropoietin has been shown to protect cardiomyocytes from ischemia-reperfusion injury in rodents.

Methods: We prospectively studied 101 patients with first MI who received successful primary PCI within 12 h from the onset of MI.