Publications by authors named "Toshihiro Ishibashi"

Background: Severe vessel tortuosity may prevent a microcatheter from reaching a distal vessel. However, the Double-Wire Technique (DWT) may facilitate the procedure. The present study evaluated the feasibility and safety of guiding a 0.

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  • - The study explored the use of a straight-shaped 3-Fr guiding sheath (GS) for endovascular treatment (EVT) via transradial artery access (TRA), focusing on patients with small radial artery diameters, specifically those under 2 mm.
  • - A total of 26 cases were treated with the 3-Fr GS, primarily addressing unruptured cerebral aneurysms and other conditions, showing a high success rate of 96.2% without any complications in the first 30 days following the procedures.
  • - The findings suggest that the 3-Fr GS is a promising option for EVT in patients with small radial arteries, enhancing safety and feasibility for treating selected vascular conditions.
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  • - The study investigates the potential risk of intraprocedural rupture (IPR) during coil embolization of ruptured intracranial aneurysms (RIAs) when using an intermediate catheter (IMC) compared to not using one.
  • - A retrospective analysis of 195 aneurysms in 192 patients over 16 years found that the incidence of IPR was significantly higher in the IMC group (14.0% vs. 3.3%) and remained higher (23.1% vs. 3.8%) even after controlling for other variables.
  • - The authors suggest that surgeons should exercise increased caution and care when using IMCs to prevent IPR during the embolization process.
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Medical illustrations represent a precious resource for learning surgical anatomy and surgical techniques, allowing preoperative and postoperative reviews. As traditional hand-drawn illustrations are difficult to use and expressing the area of neurointerventional surgery is time-consuming, we proposed methods for neurointerventional surgeons to create digital illustrations (DIs) for neurointerventional surgery using the iPad-exclusive Procreate application (Savage Interactive, Hobart, Australia). Dedicated "digital pens" were created and used for each endovascular device, creating straightforward representations of neurointerventional procedures and changes over time.

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Background: The current 3D-iFlow application can only measure the arrival time of contrast media through intensity values. If the flow rate could be estimated by 3D-iFlow, patient-specific hemodynamics could be determined within the scope of normal diagnostic management, eliminating the need for additional resources for blood flow rate estimation.

Objective: The aim of this study is to develop and validate a method for measuring the flow rate by data obtained from 3D-iFlow images - a prototype application in Four-dimensional digital subtraction angiography (4D-DSA).

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Objective: To investigate on three-dimensional (3D) fusion images the apposition of low-profile visualized intraluminal support (LVIS) stents in intracranial aneurysms after treatment and assess inter-rater reliability.

Materials And Methods: Records of all patients with unruptured intracranial aneurysms who were treated with the LVIS stent were retrospectively accessed and included in this study. Two neurosurgeons evaluated the presence of malapposition between the vessel walls and the stent trunk (crescent sign) and the vessel wall and the stent edges (edge malappostion) on 3D fusion images.

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Purpose: Although stent-assisted technique is expected to help provide a scaffold for neointima formation at the orifice of the aneurysm, not all aneurysms treated with stent-assisted technique develop complete neointima formation. The white-collar sign (WCS) indicates neointimal tissue formation at the aneurysm neck that prevents aneurysm recanalization. The aim of this study was to explore factors related to WCS appearance after stent-assisted coil embolization of unruptured intracranial aneurysms (UIAs).

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  • Advancements in high-resolution imaging and computational techniques have made clinical simulations for endovascular procedures increasingly practical, improving treatment planning for devices like virtual and braided stents.
  • The use of 3D printing for realistic simulations aids in understanding complex procedures, facilitating training for both new and experienced surgeons dealing with conditions like arteriovenous malformations.
  • Successful integration of medical and engineering approaches is critical for the future, along with necessary regulatory approvals and commercialization of these simulation technologies.
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  • Intraprocedural rupture (IPR) is a rare but serious complication that can occur during endovascular coil embolization of unruptured intracranial aneurysms (UIAs), affecting a small percentage of patients.
  • A review of 2,172 treated aneurysms found that specific risk factors, including the presence of a bleb, small neck size, and location in the posterior or anterior communicating artery, were linked to a higher chance of IPR.
  • Utilizing balloon guiding catheters (BGCs) during the procedure showed promise in significantly reducing morbidity and mortality rates in patients who experienced IPR, despite similar overall rupture rates when compared to procedures without BGCs.
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  • - The study examines the effectiveness and safety of using intermediate catheters (IMCs) in triaxial systems for coil embolization of unruptured cerebral aneurysms (UCAs) by comparing two patient groups—those with IMC and those without.
  • - A total of 2430 UCAs from 2259 patients were reviewed, revealing that patients with IMCs had a higher rate of complete occlusion and better coil packing density, with significant statistical differences noted.
  • - Overall, using IMCs during the procedure resulted in improved outcomes without increasing the risk of complications, showing IMCs provide beneficial support in treating UCAs.
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To achieve good treatment outcomes in coil embolization for cerebral aneurysms, it is important to select an appropriate 1st coil for each aneurysm since it serves as a frame to support the subsequent coils to be deployed. However, its selection as appropriate size and length from a wide variety of lineups is not easy, especially for inexperienced neurosurgeons. We developed a machine learning model (MLM) to predict the optimal size and length of the 1st coil by learning information on patients and aneurysms that were previously treated with coil embolization successfully.

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Background And Objectives: Planning/guidance software became important tools for physicians' presurgical optimal decision-making. However, there are no intracranial stent products with specifically associated simulation software. We report the "premarket" clinical trial of a new braided stent with a customized simulation software.

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Background: During coil embolization of intracranial aneurysms, the aneurysmal neck needs to be evaluated because coil protrusion into the parent artery may lead to ischemic complications. However, the neck cannot always be clearly visualized due to the limitation of the angiography system and due to the structure of the aneurysm. As a visual aid, we propose a color-coded fusion imaging method that generates "virtual coil" images using preoperative three-dimensional digital subtraction angiography (3D-DSA) images.

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Objective: Although it has been proposed that aneurysm morphology is different after rupture, detailed research of the morphological changes using 3D imaging acquired before and after rupture has not been conducted because of the difficulty of data collection. Similarly, hemodynamic changes due to morphological alterations after rupture have not been analyzed. The aim of this study was to investigate the changes in morphology and hemodynamics observed after aneurysm rupture.

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Background: The transradial approach (TRA) is less invasive than the transfemoral approach (TFA), but the higher conversion rate represents a drawback. Among target vessels, the left internal carotid artery (ICA) is particularly difficult to deliver the guiding catheter to through TRA. The purpose of this study was thus to explore anatomical and clinical features objectively predictive of the difficulty of delivering a guiding catheter into the left ICA via TRA.

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Purpose: Neurointervention via transradial access (TRA) is less invasive than via transfemoral access. However, radial artery occlusion (RAO) may occur with TRA. The purpose of this study was to explore risk factors for RAO after coil embolization of unruptured intracranial aneurysms (UIAs) via TRA.

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Background: Direct carotid-cavernous fistulas (dCCFs) are often treated endovascularly. However, because the dCCF is usually a high-flow shunt, it is often difficult to obtain an accurate vascular structure using conventional digital subtraction angiography (DSA). Here, the authors report a case of successfully treated dCCF using three-dimensional (3D) fused DSA images.

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Objective: Juvenile nasopharyngeal angiofibroma (JNA) is a very rare hemorrhagic vascular tumor that predominantly affects adolescent boys. The tumor is relatively large when detected, and the risk of intraoperative bleeding is high. We aimed to examine factors associated with intraoperative blood loss in JNA surgery.

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Purpose: Aneurysms at the origin of the fetal posterior cerebral artery (fPCA) often show fPCA bifurcation from the aneurysm dome, impeding complete embolization and dense coil packing. The recanalization rate for fPCA aneurysms is therefore high. This study aimed to evaluate the efficacy and safety of stenting into fPCA for aneurysms with fPCA incorporated into the aneurysm to determine whether stenting can provide effective embolization results and prevent recanalization.

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Background And Purpose: Large vessel occlusion (LVO) in hyperacute ischemic stroke occurs mainly by one of two mechanisms, embolism or atherosclerosis. However, the mechanism is difficult to identify prior to treatment. We aimed to investigate the factors associated with embolic LVO in hyperacute ischemic stroke, and to develop a preoperative predictive scale for the event.

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Since most unruptured intracranial aneurysms(UIA)are asymptomatic, it is important to determine treatment indications. The purpose of UIA treatment is to prevent rupture and relieve the patient's mental burden. Therefore, building a good relationship between doctors and patients is a major premise for one of the indications for surgical treatments.

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Article Synopsis
  • The study focused on creating a predictive model for recurrence of chronic subdural hematoma (CSDH) after initial surgery, finding that about 10% of patients may need reoperation.
  • Researchers analyzed pre- and postoperative CT images from 231 patients, measuring midline shift, residual hematoma thickness, and subdural cavity thickness, classifying the hematomas into different architectural subtypes.
  • The results indicated that certain CT findings, particularly preoperative midline shift and postoperative subdural cavity thickness, could effectively predict recurrence rates, achieving a model with a 0.796 area under the curve (AUC).
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Background: Transradial access (TRA) has a lower risk of access-site complications than transfemoral access but can cause major puncture-site complications, including acute compartment syndrome (ACS).

Observations: The authors report a case of ACS associated with radial artery avulsion after coil embolization via TRA for an unruptured intracranial aneurysm. An 83-year-old woman underwent embolization via TRA for an unruptured basilar tip aneurysm.

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Purpose: The transradial approach (TRA) in neuroendovascular treatment is known to have a lower risk of complications than the transfemoral approach (TFA). However, little research has focused on assessments of efficacy and risk of complications in the treatment of intracranial aneurysms. This study aimed to compare the efficacy and complications of TRA and TFA in coil embolization of unruptured intracranial aneurysms (UIAs) at our institution.

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Objectives: Methods for assessing platelet function in patients with neurovascular disease remain controversial and poorly studied. This study aimed to assess associations between thromboelastography 6s (TEG6s) measurements and postoperative ischemic complications in patients with unruptured intracranial aneurysms (UIAs) treated by coil embolization.

Methods: Eighty-four patients with UIAs taking a combined aspirin and clopidogrel protocol were retrospectively reviewed from January 2021 to May 2022.

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