Publications by authors named "Toshihide Shishido"

Article Synopsis
  • The study focused on analyzing the prognostic significance of cribriform patterns in patients with Gleason score 4 + 4 prostate cancer and their relationship to biochemical recurrence (BCR).
  • It involved 108 patients who underwent robot-assisted radical prostatectomy, measuring the total cancer area and the area of cribriform patterns on scanned tissue slides.
  • Results indicated that a higher percentage of cribriform patterns and elevated preoperative PSA levels independently predicted the risk of BCR in these patients.
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Article Synopsis
  • The study evaluated the impact of anteroposterior dissection during holmium laser enucleation of the prostate (HoLEP) on the incidence of stress urinary incontinence (SUI) post-surgery.
  • A total of 288 patients were analyzed, with 134 undergoing retrograde dissection and 154 undergoing anteroposterior dissection, revealing significant differences in SUI rates.
  • Results showed 20.1% of patients experienced SUI post-surgery, but those who had anteroposterior dissection had a lower occurrence and better early recovery rates, indicating its effectiveness in minimizing SUI risks.
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  • This study examined the link between diffusion coefficients in certain prostate lesions and significant prostate cancer within the transition zone.
  • A total of 102 patients who had biopsies for high-risk prostate lesions were analyzed, revealing a 49% cancer detection rate and that lower diffusion coefficients were associated with clinically significant cancer.
  • The findings suggest that the minimum apparent diffusion coefficient could serve as an important predictor for identifying clinically significant prostate cancer, aiding decisions on further biopsies for patients displaying these lesions.
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Objective: This study was performed to evaluate the clinical and perioperative outcomes of laparoscopic retroperitoneal lymph node dissection (L-RPLND) and open retroperitoneal lymph node dissection (O-RPLND) performed by one surgeon at a single center.

Methods: We evaluated 30 patients with stage IIA germ cell tumors who underwent retroperitoneal lymph node dissection (15 underwent L-RPLND and 15 underwent O-RPLND) at our institution between April 1, 2010 and March 31, 2018. The clinical parameters were compared between patients who underwent L-RPLND using the retroperitoneal approach and those who underwent O-RPLND using the transperitoneal approach.

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Background: For prostate cancer, accurate prediction of the pathological stage before surgery is very important. Therefore, the aim of the present study was establishing the prostate-specific antigen (PSA) threshold nomogram to predict pathologically advanced prostate cancer using the novel method of area under the receiver operating characteristic curve boosting (AUCBoost).

Methods: The medical records of patients with clinically localized prostate cancer who underwent robot-assisted radical prostatectomy were retrospectively reviewed.

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Objective: To evaluate the efficacy and safety of intravesical KRP-116D, 50% dimethyl sulfoxide solution compared with placebo, in interstitial cystitis/bladder pain syndrome patients.

Methods: Japanese interstitial cystitis/bladder pain syndrome patients with an O'Leary-Sant Interstitial Cystitis Symptom Index score of ≥9, who exhibited the bladder-centric phenotype of interstitial cystitis/bladder pain syndrome diagnosed by cystoscopy and bladder-derived pain, were enrolled. Patients were allocated to receive either KRP-116D (n = 49) or placebo (n = 47).

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Purpose: Acute pyelonephritis (APN) with obstructive uropathy is not uncommon and often causes serious conditions including sepsis and septic shock. We assessed the risk factors for septic shock in patients with obstructive APN associated with upper urinary tract calculi.

Methods: We retrospectively studied 69 patients with obstructive APN associated with upper urinary tract calculi who were admitted to our hospital.

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Background: The significance of total kidney volume (TKV) as a biomarker of kidney function in autosomal dominant polycystic kidney disease (ADPKD) is controversial and has been reappraised.

Methods: Between 2007 and 2012, 64 patients were followed with a mean 39.7-month observation period.

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Background: Vascular endothelial growth factor (VEGF) is known as one of the key molecules in molecular targeting therapy for patients with renal cell carcinoma (RCC). Several studies have shown that VEGF might be useful for predicting prognosis in RCC. We examined whether pretreatment serum VEGF can be used as a predictor of recurrence-free survival in non-metastatic RCC.

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A 24-year-old man was referred to our department for urinary retention and urinary tract infection. He was pointed out a bladder diverticulum in childhood. Computerized tomography (CT) scanning and magnetic resonance imaging (MRI) showed a bladder diverticulum, 10 by 8 cm in size, which was located posteriorly in the bladder.

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Aims: The importance of the T- and L-type Ca(2+) channels on the alpha(1)-adrenoceptor-mediated contraction of guinea-pig vas deferens was investigated in relation to the SK and BK channels.

Methods: Isometric contractile response to electrical stimulation (ES) of 50 pulses at 40 Hz was recorded. ES responses were modulated via calcium and potassium channels in the presence of purinergic inhibitors.

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Objective: We compared the surgical results between holmium laser enucleation of the prostate (HoLEP) and transurethral resection of the prostate (TUR-P) for the treatment of men with benign prostatic hyperplasia (BPH).

Methods: A total of 87 patients with symptomatic BPH were analysed. HoLEP was performed on 46 men (mean age 68.

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Diseases associated with persistent urachus are relatively rare. During the past 9-year period, there have been 14 patients with urachal disease consisting of 10 with urachal abscess and 4 with urachal cancer. The 10 patients with urachal abscess consisted of 7 males and 3 females aged 19-77 years (mean, 46 years).

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