Publications by authors named "Tosev S"

The study was aimed to determine factors of carotid intimamedia thickness (CIMT) in a population of patients with type 2 diabetes (T2D). A survey was conducted on 370 patients (mean age 60.3±8.

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In this article cases of two sisters with premature atherosclerosis have been described. The first one aged 31 with diagnosis of growth hormone deficiency (GHD) and diabetes mellitus presented with calf intermittent claudication as a result of tibial arteries occlusions. The second one aged 34 with impaired fasting glycemia and without any sign of GHD presented with sudden calf pain as a result of tibial posterior arterial acute occlusion.

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The study was aimed to define the predictors for peripheral and carotid revascularization in type 2 diabetic population. In all, 279 patients with type 2 diabetes and peripheral arterial disease were enrolled in a cohort longitudinal study. Study population was followed up for 24 months for the need and performance of peripheral or carotid revascularization.

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The scope of our study was to assess the prevalence of metabolic syndrome (MSy) and its components in the type 2 diabetic population with symptomatic coronary artery disease in a sample of the Macedonian population. 327 pts with type 2 diabetes and manifested coronary artery disease were randomly included in a survey. MSy was defined according ATP III criteria.

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Endothelial dysfunction, per se, in coronary arteries can stratify a risk in coronary artery disease patients. Selected studies evaluating endotheliopathy as predictor of events in patients with type 2 diabetes, but without coronary artery disease. We hypothesized that peripheral endothelial dysfunction could predict prognosis of type 2 diabetic patients who presented coronary artery disease.

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The aim of this study is to identify the risk factors for development of chronic critical limb ischemia (CLI) in diabetic and nondiabetic patients with peripheral arterial disease (PAD). 127 patients (pts) with PAD (63 with type 2 diabetes and 64 nondiabetic) were randomly included in a cross sectional study. Out of them 17 were with CLI.

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Objectives: The goal of our study was to evaluate the value of fibrinogen, D-Dimers and antithrombin III plasma levels to prognosticate mortality in patients suffering from both peripheral artery disease (PAD) and coronary artery disease (CAD).

Material And Methods: 90 patients with coexistent PAD and CAD were inrolled in 36 months study and evaluated for the following parameters: age, sex, current smoking, ankle-brachial index, claudicating distance, ejection fraction, triglycerides, cholesterol, LDL, fibrinogen, D-Dimers, antithrombin III, creatinin, glycaemia, histories of myocardial infarction, stroke, diabetes and previous revascularization, as well as number of other concurrent diseases. We developed linear regression model for identification of variables, associated with cardiovascular events, and multivariate regression model to define the predictors of mortality.

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Unlabelled: The goal of our study was to evaluate the value of fibrinogen, D-dimers and antithrombin III plasma levels in prognosticating mortality in patients suffering from both peripheral arterial disease (PAD) and coronary artery disease (CAD).

Patients And Methods: 90 patients with coexistent PAD and CAD were enrolled in a 36 months study, and evaluated for the following parameters: age, sex, current smoking, ankle-brachial index, claudicating distance, ejection fraction, triglycerides, cholesterol, LDL, fibrinogen, D-Dimers, antithrombin III, creatinine, glycaemia, histories of myocardial infarction, stroke, diabetes and previous revascularization, as well as a number of other concurrent diseases. We developed a linear regression model for identification of variables, associated with cardiovascular events, and a multivariate regression model to define the predictors of mortality.

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