Publications by authors named "Toru Tonoike"

Article Synopsis
  • Western treatment guidelines usually suggest biguanides as the first option for diabetes, but in Japan, DPP-4 inhibitors are also becoming popular as initial therapy for type 2 diabetes (T2DM).
  • A study was conducted from 2012 to 2021 to compare the effectiveness and long-term costs of biguanides versus DPP-4 inhibitors in patients starting treatment for T2DM.
  • Results showed no significant differences in health outcomes or complications between the two treatments, but biguanides were found to be significantly cheaper on a daily cost basis.
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