Magnitude of neonatal sepsis and its associated factors among neonates admitted to the neonatal intensive care unit in Hawassa Comprehensive Specialized Hospital, Sidama Regional State, Ethiopia, 2020.

Background: Neonatal sepsis is one of the most common causes of disease and death among neonates globally. And it made a great contribution to neonatal admission to intensive care units. To mitigate the ongoing neonatal crisis and accomplish the goal of sustainable development through a decrease in neonatal mortality, information from various regions is needed.

Evaluating quality of contraceptive counseling using SERVQUAL model: A cross-sectional study in southern Ethiopia, 2021.

Background: Providing quality contraceptive counseling services is essential to support mothers in using modern contraceptives that meet their needs. However, the quality of service provision has not been evaluated in a study setting.

Objective: This study aimed to assess the quality of contraceptive counseling using a service quality model in southern Ethiopia.

Assessment of Low Birth Weight and Associated Factors Among Neonates in Butajira General Hospital, South Ethiopia, Cross Sectional Study, 2019.

Background: Low birth weight is defined as when a newborn weighs less than 2,500 grams within an hour of birth. Globally, it has been known that around 15.5% of newborns were below the normal level of weight at their birth and 95% of these infants lived in developing countries.

Carbon stock under major land use/land cover types of Hades sub-watershed, eastern Ethiopia.

Background: Developing land management scenarios that have the potential to sequester carbon and reduce greenhouse gasses (GHG) emission on a sustainable basis entails quantifying the current carbon stock under different land uses. In light of this, a study was conducted in Hades sub-watershed, eastern Ethiopia, to explore the carbon stock under four major land uses: natural forest, coffee agroforestry, grazing land and cropland, involving samples from four carbon pools: aboveground, belowground, litter, and soil. To this end, vegetation and soil samples were collected from the respective land uses following recommended procedures.

Magnitude of postpartum depression and associated factors among women in Mizan Aman town, Bench Maji zone, Southwest Ethiopia.

Background: The first 12 months after childbirth may represent a high-risk time for depression. In Ethiopia there is a paucity of evidence about its magnitude and associated factors during that period. So, the aim of this study was to assess the magnitude of depression and associated factors among postpartum women in Mizan Aman town, Bench Maji Zone, Southwest Ethiopia 2017.

Inflammatory mediators in chronic heart failure in North India.

Introduction: Recent evidence shows that pro-inflammatory cytokines may be important in the assessment of severity and prognosis in congestive heart failure (CHF). In the present study, we examine the association of cytokines with causes, grade and prognosis of CHF patients.

Subjects And Methods: Of 127 patients with CHF, 11 were excluded and the remaining 116 patients with different aetiologies of CHF, and 250 age- and sex-matched control subjects, were evaluated in this case study.

Synthesis and configurational stability of (S)- and (R)-deuteriothalidomides.

3'-Deuteriothalidomide was synthesized and found to be configurationally five times more stable than thalidomide toward racemization at physiological pH.

Poly[(3-hexylthiophene)-block-(3-semifluoroalkylthiophene)] for polymer solar cells.

We report the synthesis of poly[(3-hexylthiophene)-block-(3-(4,4,5,5,6,6,7,7,7-nonafluoroheptyl)thiophene)], P(3HT-b-3SFT), carried out by the Grignard Metathesis Method (GRIM). The copolymers composition was determined by (1)H and (19)F NMR spectroscopies, and gel permeation chromatography (GPC). The thin films of P(3HT-b-3SFT) were investigated by ultraviolet-visible absorption spectroscopy and atomic force microscopy (AFM).

Catalytic enantioselective hydrophosphonylation of ketimines using cinchona alkaloids.

Organocatalytic enantioselective hydrophosphonylation of ketimines using cinchona alkaloids and Na(2)CO(3) afforded products with high enantioselectivity. Both enantiomers of alpha-amino phosphonates can be prepared by using pseudoenantiomeric cinchona alkaloids. The catalyst loading of cinchona alkaloids can be reduced to 0.

Cytotoxic effect of amide derivatives of trifluoromethionine against the enteric protozoan parasite Entamoeba histolytica.

Amoebiasis, caused by infection with the enteric protist Entamoeba histolytica, is one of the major parasitic diseases. Although metronidazole and its derivatives are currently employed in therapy, the paucity of effective drugs and potential clinical resistance necessitate the development of a novel drug. Trifluoromethionine (TFM) is a promising lead compound for antiamoebic drugs.

Enantioselective electrophilic trifluoromethylation of beta-keto esters with Umemoto reagents induced by chiral nonracemic guanidines.

Chiral nonracemic guanidines act as Brønsted bases to generate guanidinium enolates for the enantioselective electrophilic trifluoromethylation of beta-keto esters by means of S-(trifluoromethyl)dibenzothiophenium tetrafluoroborate (Umemoto reagent) with good enantioselectivity of 60-70% range. Despite the fact that the ees are still improvable, the model reported in this work could spark the imagination of chemists to design new chiral bases to improve the stereochemical outcome.

New diarylmethanofullerene derivatives and their properties for organic thin-film solar cells.

A number of diarylmethanofullerene derivatives were synthesized. The cyclopropane ring of the derivatives has two aryl groups substituted with electron-withdrawing and -donating groups, the latter with long alkyl chains to improve solubility in organic solvents, an important property in processing cells. First reduction potentials of most derivatives were less negative than that of [6,6]-phenyl-C61-butyric acid methyl ester (PCBM), which is possibly ascribed to their electron-withdrawing nature.

Synthesis of trifluoroethoxy-coated binuclear phthalocyanines with click spacers and investigation of their clamshell behaviour.

We disclose here the synthesis of a novel trifluoroethoxy-coated binuclear Pc which is the first example of a never-closing clamshell Pc.

Synthesis, configurational stability and stereochemical biological evaluations of (S)- and (R)-5-hydroxythalidomides.

The first asymmetric synthesis of (S)- and (R)-5-hydroxythalidomides, one of thalidomide's major metabolites, was achieved using HMDS/ZnBr(2)-induced imidation as a key reaction. 5-Hydroxythalidomide was found to be configurationally more stable than thalidomide at physiological pH. Stereochemical biological effects of thalidomide and 5-hydroxythalidomide on anti-angiogenesis and antitumor activities were also investigated using racemic and pure enantiomers.

Synthesis of covalently linked binuclear clamshell phthalocyanine by double-click reaction.

A novel covalently linked binuclear phthalocyanine 1 was synthesized by the "double-click" reaction. The UV-vis and fluorescence spectra and electrochemistry revealed that the geometry of 1 is a closed clamshell conformation in which a strong electronic interaction is observed between the two Pc moieties.

DBFOX-Ph/metal complexes: evaluation as catalysts for enantioselective fluorination of 3-(2-arylacetyl)-2-thiazolidinones.

We examined the catalytic enantioselective fluorination of 3-(2-arylacetyl)-2-thiazolidinones 1 with N-fluorobenzenesulfonimide (NFSI) by DBFOX-Ph/metal complexes under a variety of conditions. After optimization of the metal salts, solvents and additives, we found that the fluoro-2-thiazolidinones 2 were obtained in good to high yields with moderate to good enantioselectivities (up to 78% ee) when the reaction was carried out in the presence of DBFOX-Ph (11 mol%), Ni(ClO(4))(2).6H(2)O (10 mol%) and 2,6-lutidine (0 or 1.

Synthesis and properties of trifluoroethoxy-coated binuclear phthalocyanine.

A genuine example of non-aggregated highly fluorescent binuclear phthalocyanines is reported; spectroscopic studies and computations revealed that the two halves of trifluoroethoxy-coated binuclear phthalocyanine are rotated in the same directions so as to contact each other as much as possible.

Catalytic and highly enantioselective reactions of alpha-sulfonyl carbanions with chiral bis(oxazoline)s.

The enantioselective reactions of lithiated benzyl trifluoromethyl sulfones with a substoichiometric amount of a bis(oxazoline) and various aldehydes is disclosed. The products were formed with excellent diastereo- and enantioselectivities. Fluorination of the sulfone with N-fluorobenzenesulfonimide and a stoichiometric amount of a bis(oxazoline) gave products with extremely high enantioselectivities (up to 99% ee; ee=enantiomeric excess).