Publications by authors named "Toru Sato"

Proximal femoral fractures (PFFs) among individuals aged ≥90 years are becoming more common with an aging population and are associated with high morbidity and mortality. This study analyzed the prognostic factors influencing survival in nonagenarian patients undergoing surgery for PFFs. We enrolled 285 patients who underwent surgery between 2016 and 2022.

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  • * She had a splenectomy to address her thrombocytopenia caused by an enlarged spleen (hypersplenism), but nine months later, she experienced exertional dyspnea and was diagnosed with portopulmonary hypertension (PoPH).
  • * Treatment with the medication macitentan improved her symptoms and right heart pressure readings, marking a rare case of PoPH arising after splenectomy.
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  • * Out of 1507 cancer patients studied, 4.7% experienced an ischemic stroke over a median follow-up of 1020 days, with a cumulative incidence of 4.0% at 1 year.
  • * Key risk factors for stroke include specific cancers (pancreatic, ovarian, lung), dyslipidemia, metastasis, elevated D-dimer levels, and younger age, highlighting the need for vigilant monitoring in these patients.
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  • The study examined the risk of recurrent venous thromboembolism (VTE) in patients with isolated distal deep vein thrombosis (DVT) who might experience thrombosis extension under different treatment regimens.
  • Conducted in Japan from April 2019 to April 2022, the trial involved 87 patients who received either rivaroxaban with physical therapy or physical therapy alone for 90 days, monitoring for VTE recurrence and major bleeding.
  • Results showed that the rivaroxaban group had no cases of VTE recurrence, while the physical therapy group had a 4.4% recurrence rate; however, rivaroxaban was associated with a higher incidence of major bleeding events (9.5%).
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Background An increased risk of anemia during edoxaban thromboprophylaxis in orthopedic surgery has been reported. However, the risk factors for the exacerbation of anemia requiring transfusion with irradiated red blood cell concentrates during postoperative edoxaban thromboprophylaxis remain unknown. Therefore, this study investigated the factors that increase the possibility of transfusion during edoxaban thromboprophylaxis after orthopedic surgery by reanalyzing clinical data from a previous collection.

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  • - The study investigated how well resin abutments on endodontically treated roots resist fractures, using both static and cyclic loading tests.
  • - Bovine roots were modified with varying remaining coronal tooth coverage, and it was found that covering half of the circumference increased static fracture loads and survival rates.
  • - The placement of the remaining coronal tooth impacted the fracture resistance, with specific configurations improving resistance to both static and dynamic fractures.
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Purpose: Dynamic chest radiography using X-ray fluoroscopic video analysis has shown potential for the diagnosis of pulmonary embolism (PE), but its diagnostic performance remains uncertain. We aimed to evaluate the diagnostic performance of fluoroscopic video analysis for diagnosing PE.

Methods: A prospective single-center observational study was conducted between October 2020 and January 2022.

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  • Treponema denticola is linked to chronic periodontitis, and the study examines the role of the gene TDE_0259 (oxtR1) in its environmental adaptability.
  • Using an oxtR1-deficient mutant, researchers found that inactivating oxtR1 sped up bacterial growth and altered its susceptibility to antibacterial agents, revealing changes in gene expression related to stress response mechanisms.
  • The study concludes that OxtR1 is an oxygen-sensing regulator that influences genes for ferrodoxin and likely helps T. denticola cope with oxygen-related stresses.
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  • The study introduces a new method for measuring how hydrate particles behave in gas flows, which is important for natural gas transport.
  • It features a closed-flow loop system powered by an internal fan that allows for continuous observation and manipulation of small hydrate particles (10-50 μm) in the gas flow.
  • The effectiveness of this setup is validated through visual observations and by using a computational model to simulate and analyze the flow of particles.
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Introduction: There is limited data on the safety of direct oral anticoagulants (DOACs) in fragile patients with venous thromboembolism (VTE).

Materials And Methods: We used the COMMAND VTE Registry-2 enrolling patients with acute symptomatic VTE. The study population consisted of 3928 patients receiving DOACs, who were divided into fragile (2136 patients) and non-fragile groups (1792 patients).

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Unlabelled: Prompt termination of pregnancy in patients with decompensated pulmonary arterial hypertension (PAH) is imperative for improvement of maternal hemodynamics, but such termination may also result in maternal death due to further deterioration of PAH immediately after delivery. However, there have been limited reports on whether implementation of PAH therapy with continuation of pregnancy improves the maternal outcome, especially in treatment-naïve patients with PAH. A 24-year-old woman was admitted to our hospital with a chief complaint of dyspnea (WHO functional class IV) at 22 weeks and 3 days of gestation.

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Background: In acetabular fracture surgery, an infra-acetabular screw (IAS) is inserted from the anterior to the posterior column through the infra-acetabular corridor to stabilize both columns. Although the IAS is useful for increasing fixation strength, proper placement requires proficiency and often results in extraosseous screw penetration. The complex anatomy of the infra-acetabular corridor and difficult intraoperative detection of the ideal insertion point and angle make proper placement of the IAS challenging.

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In mouse dentate gyrus, radial glia-like cells (RGLs) persist throughout life and play a critical role in the generation of granule neurons. A large body of evidence has shown that the combinatorial expression of transcription factors (TFs) defines cell types in the developing central nervous system (CNS). As yet, the identification of specific TFs that exclusively define RGLs in the developing mouse dentate gyrus (DG) remains elusive.

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  • This study assessed how different scanning pathways during optical impression affect the accuracy (trueness) and consistency (precision) of full-arch dental impressions.
  • The research used a laboratory scanner to gather reference data and compared it to impressions taken with a TRIOS® 3 scanner using various pathways; findings indicated no significant differences in scanning time or trueness among the pathways.
  • However, precision measurements showed significant variations between certain pathways for both starting and ending sides, with notable error ranges observed in specific regions of the dental arch using color map imagery.
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Knee arthroplasty, both total knee and unicompartmental, has had a significant impact on millions of patients globally. Although satisfaction is usually high, complications such as periprosthetic fracture are increasingly common. Distal femur periprosthetic fractures are relatively well researched and understood in comparison with periprosthetic proximal tibia fractures (PTFs).

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  • * The study found that full-sized dentipain and a truncated version are located in the outer sheath derived from specific T. denticola mutants, suggesting that dentilisin and Msp assist in dentipain's secretion and maturation.
  • * Inactivating the dentipain gene reduces T. denticola growth, affects gene expression related to transport and chemotaxis, and lowers its ability to adhere and autoaggregate, indicating that dentipain
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Edoxaban (Edx) has been approved to prevent venous thromboembolism after total knee and/or hip arthroplasty in Japan. However, the risk of anemia with Edx treatment remains elusive. No risk factors for Edx-associated anemia after orthopedic surgery have been reported.

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  • The paper discusses the analytic structure of the three-channel S matrix by creating a single-valued mapping using uniformization techniques, with a focus on transformations in the complex energy plane.
  • The authors utilize the Mittag-Leffler expansion for the three-channel scattering amplitude, highlighting both trivial and nontrivial contributions linked to the Weierstrass zeta function.
  • Through a case study with a nonrelativistic effective field theory, they illustrate that the scattering amplitude aligns with the Mittag-Leffler expansion, showing significant effects from adjacent poles.
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  • Marine debris, which travels long distances and collects on shorelines, poses a significant environmental issue, especially along the Singapore coast.
  • The study aimed to pinpoint the sources of this debris using advanced methods and data from local beach clean-up volunteers, revealing a popular tourist area as a key contributor.
  • Findings suggest that citizen science data can aid in ongoing monitoring and inform policy decisions, with suggestions for future research to incorporate factors like monsoons and sudden debris release events.
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Detecting early-stage oral cancer and precancerous lesions are critical to improving patient prognosis and quality of life after treatment. Photodynamic diagnosis using 5-aminolevulinic acid enables the detection of malignant lesions. This study aimed to improve the diagnostic accuracy of photodynamic diagnosis using an objective chromaticity analysis of fluorescence emitted from oral lesions.

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Background: Aortic valve stenosis (AS) leads to increased cardiovascular mortality and morbidity, and recent studies reported that even mild-to-moderate AS was associated with poor prognosis in the general population. This study investigated the prognostic impact of mild or moderate AS, defined as 2.0 m/s ≤ peak aortic jet velocity (Vmax) ≤3.

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The purpose of this study was to evaluate whether change in cuspal inclination influences the fracture load values of composite resin computer-aided design/computer-aided manufacturing (CAD/CAM) crowns. Abutment teeth and CAD/CAM crowns were prepared as they would be for treating a mandibular first premolar with two cusps. The CAD/CAM crowns were designed so that 1) the principal stress lines would be radially distributed from the two points of contact with the indenter to the occlusal area of the abutment (Type I), or 2) the principal stress lines would pass outside the occlusal area of the abutment (Types II and III).

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Layered-type zirconia disks, which offer color gradation from enamel to cervical shade, have been employed in recent years to replicate the shades of natural teeth. The layered structure is effective at replicating colors and has helped popularize monolithic zirconia restorations. However, the sintering shrinkage of zirconia is very large; thus, controlling the sintering distortion is very important.

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  • * Patients with DVT were found to have lower body weight and higher levels of D-dimer and IMPROVE VTE scores, indicating a correlation between these factors and DVT risk.
  • * The findings suggest that psychiatric patients recovering from COVID-19 are at an increased risk for DVT, highlighting the need for careful monitoring and follow-up care.
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