[Long-Covid: On the Genealogy of a New Disease and a Chance of a Cultural Sociological (Research) Perspective].

The article deals with the question of how Long Covid has become a disease. Of interest are the pathways and imprints, how the problem has established itself as a disease and materialized, or how society has come to the realization of its problems. Far-reaching institutionalization of Long Covid as a disease belies existing interpretive struggles in and around Long-Covid.

Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease.

The overlapping clinical features of relapsing remitting multiple sclerosis (RRMS), aquaporin-4 (AQP4)-antibody (Ab) neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein (MOG)-Ab disease mean that detection of disease specific serum antibodies is the gold standard in diagnostics. However, antibody levels are not prognostic and may become undetectable after treatment or during remission. Therefore, there is still a need to discover antibody-independent biomarkers.

Tetrakis(diisopropyl amide) substituted norbornadiene and quadricyclane are highly barium selective ligands.

Tetrakis(diisopropyl amide) substituted norbornadiene and quadricyclane derivatives were investigated for their extraction and transport capabilities with alkaline earth metal cations. Both amides exhibited a remarkably high preference of Ba(2+) over any other alkali metal or alkaline earth cation. The binding geometries were determined by quantum chemical DFT calculations.