Publications by authors named "Torres Herran Germaine Eleanor"
Impact of Rituximab on relapse rate and disability in an Ecuadorian cohort of patients with neuromyelitis optica spectrum disorders.
Edgar Patricio Correa-Díaz Germaine Eleanor Torres-Herrán Joselyn Elizabeth Miño Zambrano Víctor Paredes-Gonzalez Francisco José Caiza-Zambrano
Mult Scler Relat Disord
February 2021
Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is a severe inflammatory demyelinating disease of the central nervous system that often causes disability. Based on evidence from prospective and retrospective studies, Rituximab (RTX) has been used as the first-line of therapy in NMOSD. Nevertheless, evidence of the impact of RTX on relapse rate and disability in Ecuadorian patients with NMOSD is lacking.
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- NMOSD is a serious central nervous system disease mainly affecting women, with a prevalence of 15.9% among inflammatory demyelinating diseases in Ecuador.
- Applying the 2015 diagnostic criteria led to a faster diagnosis and identified 24% of patients who were previously unrecognized as having NMOSD.
- The most common symptoms at disease onset were optic neuritis and acute transverse myelitis, with 88% of patients experiencing recurrent episodes.
Background: Creutzfeldt-Jakob disease is a rare and fatal neurodegenerative disorder that affects mammals and humans. The prevalence of this disease in the United States is 0.5 to 1 per million inhabitants.
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