A hybrid system of mixture models for the prediction of particle size and shape, density, and flowability of pharmaceutical powder blends.

This paper presents a system of hybrid models that combine both mechanistic and data-driven approaches to predict physical powder blend properties from their raw component properties. Mechanistic, probabilistic models were developed to predict the particle size and shape, represented by aspect ratio, distributions of pharmaceutical blends using those of the raw components. Additionally, the accuracy of existing mixture rules for predicting the blend's true density and bulk density was assessed.

First Report of Zoonotic Genotype of in Mussels () from Patagonia Argentina.

Blue mussels () are among the most consumed fishery products globally. Foodborne outbreaks of mussel-associated infections by viral, bacterial, and parasitic pathogens have been reported in the last years. In this study, we investigated the occurrence, genetic diversity, and zoonotic potential of the diarrhea-causing enteric protozoan in blue mussels from Caleta Córdova in Chubut Province, southeast Patagonia, Argentina.

Dispersion of eggs from infected dogs under natural conditions in Patagonia, Argentina.

Cystic echinococcosis caused by Echinococcus granulosus is a major zoonosis of public health significance in the Patagonian region of Argentina. This investigation sought to test the hypothesis that the persistence and dispersion of the parasite eggs can be explained by physical and meteorological parameters along with final host infection and behaviour. This observational study was carried out over a five-year period within an enclosure where two dogs harbouring a worm burden ranging from 100 to 1000 mature adult E.

Use of chemometrics in the chemical and microbiological characterization of composts from agroindustrial wastes.

Physico-chemical, chemical and microbiological parameters were studied in a set of fifteen different composts elaborated with agroindustrial wastes using two different composting systems (turning and static pile composting). To carry out the chemometric evaluation, multivariate statistical analysis techniques, such as hierarchical cluster analysis (HCA) and factorial analysis (FA) were used. Composts obtained showed suitable physico-chemical and chemical properties for their use as organic amendment and a good maturity degree.

An eco-epidemiological study of contamination of soil with infective forms of intestinal parasites.

The objectives of the present work were to screen topsoil samples collected from public squares in two cities within the Argentine Patagonia for the presence of infective forms of intestinal parasites and to examine the possible relationship between positive findings and the environmental, socioeconomic, and cultural conditions of that region. For this purpose we studied 13 public squares, their 13 custodians, and 44 family groups within their respective surrounding areas. Of the 226 topsoil samples analyzed, 44.

Presence and persistence of intestinal parasites in canine fecal material collected from the environment in the Province of Chubut, Argentine Patagonia.

We investigated the presence of intestinal parasites in canine feces collected from public squares in Comodoro Rivadavia, Chubut, Argentina (45 degrees S, 68 degrees W) and determined the persistence of Echinococcus granulosus eggs in those droppings under natural environmental conditions in that region. In the first experiment, we analyzed 163 fecal samples collected from urban squares during 8 months time and found parasitic elements in 46.6%.