Novel estimation of African swine fever transmission parameters within smallholder villages in Lao P.D.R.

African Swine Fever (ASF) disease transmission parameters are crucial for making response and control decisions when faced with an outbreak, yet they are poorly quantified for smallholder and village contexts within Southeast Asia. Whilst disease-specific factors - such as latent and infectious periods - should remain reasonably consistent, host, environmental and management factors are likely to affect the rate of disease spread. These differences are investigated using Approximate Bayesian Computation with Sequential Monte-Carlo methods to provide disease parameter estimates in four naïve pig populations in villages of Lao People's Democratic Republic.

Revisiting the Importance of Orthobunyaviruses for Animal Health: A Scoping Review of Livestock Disease, Diagnostic Tests, and Surveillance Strategies for the Simbu Serogroup.

Orthobunyaviruses (order , family ) in the Simbu serogroup have been responsible for widespread epidemics of congenital disease in ruminants. Australia has a national program to monitor arboviruses of veterinary importance. While monitoring for Akabane virus, a novel orthobunyavirus was detected.

Assessing risks for bovine and zoonotic tuberculosis through spatial analysis and a questionnaire survey in Fiji - A pilot study.

causes tuberculosis in cattle and when transmitted to humans typically causes extra-pulmonary tuberculosis (EPTB). Bovine tuberculosis (bTB) has a global distribution and is controlled in most countries to protect animal and public health. Recent studies revealed that bTB is established on dairy farms in Fiji where EPTB cases have been reported in people.

Association between major histocompatibility complex haplotypes and susceptibility of unvaccinated and vaccinated cattle to paratuberculosis.

Bovine Johne's disease (BJD) or paratuberculosis is caused by Mycobacterium avium spp. paratuberculosis (MAP) and is a worldwide problem among domestic and wild ruminants. While vaccines are available, natural differences in background immunity between breeds within species and between individuals within herds suggest that genetic differences may be able to be exploited in marker-assisted selection as an aid to disease control.

Striving for long term sustainability - Is it time we changed our approach to animal health in low- and middle-income countries?

Animal health and agricultural productivity in low- and middle-income countries have been the focus of research for development (R4D) projects for decades, with varying levels of success when considering the long-term sustainability of interventions. Many of these projects have been funded, designed and implemented by researchers from high income countries, and therefore risk neglecting the cultural nuances and complex country histories that can influence their success. This opinion piece suggests three broad recommendations: (1) implementing culturally congruent practices to improve disease control and prevention practices at the village level; (2) promoting public-private partnerships to improve control of transboundary animal diseases; and (3) improving national animal health and veterinary services and their governance to improve disease surveillance, control and prevention.

Intercolonial Microdamage and Cracking Micromechanisms during Wire Drawing of Pearlitic Steel.

This paper studies the drawing-induced intercolonial microdamage (ICMD) in pearlitic microstructures. The analysis was performed from the direct observation of the microstructure of the progressively cold-drawn pearlitic steel wires associated with the distinct steps () of a real cold-drawing manufacturing scheme, constituted by seven cold-drawing passes. Three types of ICMD were found in the pearlitic steel microstructures, all affecting two or more pearlite colonies, namely: (i) ; (ii) ; and (iii) .

Stress Intensity Factor (SIF) Solutions and Fatigue Crack Paths in Eccentric Circumferentially Cracked Round Bar (CCRB) in Tension.

In this paper, a numerical modeling was developed to study (on the basis of the Paris law) the fatigue propagation paths of eccentric external (outer) cracks in circumferentially cracked round bars (CCRB) subjected to a cyclic type of loading in the form of either or . Results show how the eccentricity (in relation to the wire axis) of the circular resistant ligament increases with the growth of outer circumferential cracks by subcritical fatigue mechanisms. This phenomenon is more pronounced when the solicitation consists of a remote tensile loading than when it is an axial displacement, when the initial eccentricity of the ligament increases (for a given initial diameter), and when the Paris exponent characteristic of the material rises.

Utilising abattoir sero-surveillance for high-impact and zoonotic pig diseases in Lao PDR.

National disease surveillance systems are essential to a healthy pig industry but can be costly and logistically complex. In 2019, Lao People's Democratic Republic (Lao PDR) piloted an abattoir disease surveillance system to assess for the presence of high impact pig diseases (HIPDs) using serological methods. The Lao Department of Livestock and Fisheries (DLF) identified Classical Swine Fever (CSF), Porcine Respiratory and Reproductive Syndrome (PRRS) and as HIPDs of interest for sero-surveillance purposes.

Community engagement strengthens pig disease knowledge and passive surveillance in Timor-Leste.

Smallholder pig production in Timor-Leste is culturally and economically important for most households. However, regular and ongoing disease surveillance and pig husbandry training for farmers are limited. This article describes collaborative social and diagnostic research followed by a pilot community engagement program to improve farmer and technician knowledge, skills, and working relationships.

Notch Effects on the Stress Intensity Factor and on the Fatigue Crack Path for Eccentric Circular Internal Cracks in Elliptically Notched Round Bars under Tensile Loading.

In this paper, stress intensity factor (SIF) solutions are numerically obtained for notched bars subjected to tensile loading containing an eccentric circular inner crack located in the cross-section corresponding to the notch root. The finite element method and the -integral have been used to obtain the SIF and to analyze the effect on it of three elliptical notch geometries (of equal radial depth). The results show how the SIF is greater in the notched bars than in the smooth bar and within the former when the axial semi-axis of the notch rises, its effect being greater as the diameter and eccentricity of the inner crack increase.

On the Use of Multi-Step Dies for Improving the Performance against Hydrogen Embrittlement of Cold Drawn Prestressing Steel Wires.

The main cause of in-service failure of cold drawn wires in aggressive environments is hydrogen embrittlement (HE). The non-uniform plastic strains and residual stresses generated after cold drawing play a significant role in the matter of HE susceptibility of prestressing steels. In this paper, a new and innovative design of the drawing scheme is developed, geared towards the reduction in both manufacturing-induced residual stresses and plastic strains.

Innovative Design of Residual Stress and Strain Distributions for Analyzing the Hydrogen Embrittlement Phenomenon in Metallic Materials.

Round-notched samples are commonly used for testing the susceptibility to hydrogen embrittlement (HE) of metallic materials. Hydrogen diffusion is influenced by the stress and strain states generated during testing. This state causes hydrogen-assisted micro-damage leading to failure that is due to HE.

Re-Examining Cannabidiol: Conversion to Tetrahydrocannabinol Using Only Heat.

In the last decade, the market for Cannabidiol (CBD) has grown to become a near $2 billion dollar industry in the United States alone. This growth can be attributed to a growing social acceptance of marijuana, a more detailed understanding of many health benefits attributed to cannabinoids, and the low cost and wide availibility of hemp-derived cannabinoids. Due to the complex legal histories of marijuana and cannabinoids, the stability and safety of CBD is still an area of interest as research has been restricted globally.

Bovine tuberculosis control in Fiji: Retrospective study findings for 2015 to 2020.

Control of bovine tuberculosis (bTB) is a priority for animal health, biosecurity, and human health authorities in Fiji as evident from the long-term funding of the Bovine Brucellosis and Tuberculosis Eradication and Control program (BTEC) and notable improvements to the program described in this paper. To evaluate the performance of the Fiji BTEC program from 2015 to 2020, all available bTB data for cattle were analyzed. Data sources included BTEC bTB testing records, abattoir records and laboratory records.

Design and Evaluation of the Veterinary Epidemiology Teaching Skills (VETS) Workshop: Building Capacity in the Asia-Pacific Region.

Building workforce capacity in epidemiology skills for veterinarians in the Asia-Pacific region is crucial to health security. However, successful implementation of these programs requires a supply of trained veterinary epidemiology teachers and mentors. We sought to design and evaluate delivery of a 4-day Veterinary Epidemiology Teaching Skills (VETS) workshop as part of a larger project to strengthen field veterinary epidemiology capacity.

Ten years of pediatric congenital heart disease surgery in a Caribbean nation.

Background: Socioeconomical limitations in developing countries make congenital heart disease surgery (CHDs) a challenge that often relays on humanitarian efforts. We aimed to describe the evolution of an established pediatric CHDs program in the Dominican Republic and the impact of international medical missions (IMM) on its sustainability.

Methods: Data of cases operated from 2009 to 2018 were analyzed using Pearson's chi-squared test to study trends between a 5-year implementation period (T1) January 2009-December 2013, and subsequent consolidation (T2) January 2014-December 2018.

Unpacking the Theory Behind One Health Food Safety Programs: A Vietnam Case Study.

Many One Health programs are inherently complex, characterized by multiple perspectives from multiple sectors, delivery across various scales, and a focus on complex problems at the convergence of people, animals, and the environment. This complexity makes them difficult to conceptualize, requiring frameworks to organize the different program components. Evaluation frameworks that unpack the sequence of events linking program activities to outcomes (e.

Changes in farmer animal health and biosecurity knowledge, attitudes and practices: Insights from Cambodia and Laos.

Livestock agriculture in Cambodia and Laos is severely affected by endemic and exotic transboundary animal diseases, impacting household livelihoods and food and nutritional security. Collaborative animal health and biosecurity projects were conducted in each country between 2015 and 2019 aimed at increasing smallholder livestock production through mainly knowledge-based interventions in large ruminant disease prevention, nutrition, reproduction and marketing access. This study's objectives were to identify baseline animal health and biosecurity knowledge, attitudes and practices (KAP) of farmers, and temporal changes in key attitudes and practices associated with improved knowledge.

Global health security must embrace a One Health approach: Contributions and experiences of veterinarians during the COVID-19 response in Australia.

SARS-CoV-2, a betacoronavirus of likely zoonotic origin, was first reported in December 2019. Its rapid worldwide spread precipitated a range of interventions, including by veterinarians, due to impacts on human health and well-being as well as animal health and welfare. We conducted 36 key informant interviews to explore the responses of Australian veterinarians, their engagement in One Health collaboration and cooperation, and their existing and developed insights to the COVID-19 pandemic.