Publications by authors named "Tore Lier"

Article Synopsis
  • Scientists studied how certain germs spread in Norway using advanced tests to check human and animal samples for infections.
  • Most of the germs were found in kids and young adults, especially during late summer and early autumn, with 10 different types identified in people's samples.
  • They discovered some small outbreaks, like one in a kindergarten, and found that most cases were caused by a couple of common germ types that were mostly spread in the country rather than from abroad.
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Article Synopsis
  • Alveolar echinococcosis is a serious parasitic disease caused by the Echinococcus multilocularis larva, primarily affecting the liver and presenting with tumor-like growths.
  • Although mainland Norway is generally free from this infection, it can occasionally be introduced from areas where the disease is more common.
  • The review covers the life cycle of the parasite, symptoms, diagnosis and treatment options, including surgery and medication, and includes case studies of two patients affected by the disease.
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Background: Cystic echinococcosis is a zoonosis caused by the parasite Echinococcus granulosus. The disease rarely occurs in Norway, but constitutes a significant global health issue.

Case Presentation: A man in his forties presented with right-sided flank pain.

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Background: A young boy presented with acute ethmoiditis and recurrent periorbital swelling. The periorbital swelling was confirmed to be caused by a rare condition.

Case Presentation: Debut symptoms were acute rhinitis, unilateral periorbital swelling, fatigue, and swelling in the temple region, probably caused by an insect bite.

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We describe a newborn infant with hydrocephalus and a ventriculoperitoneal shunt infection caused by Brevibacterium casei. Essential for correct diagnosis was rapid species identification by matrix-assisted laser desorption/ionization time-of-flight, after initial report of coryneform bacteria. The patient responded well to vancomycin and rifampicin for 15 days.

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Background: Schistosomiasis is a tropical infectious disease in which early diagnosis and treatment can prevent serious illness. This study examined the incidence and diagnosis of schistosomiasis in Norwegian exchange students who had been exposed to freshwater in Africa.

Material And Method: Students (n = 318) from Bergen and Oslo who had travelled to Africa as part of an exchange programme in the period 2003-18, were contacted and included in the study if they had been exposed to freshwater during their stay.

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Background: Leishmaniasis is a rare but potentially severe tropical infectious disease, and Norwegian clinicians are generally unfamiliar with its diagnosis and treatment. This study aimed to investigate the number of cases diagnosed, performance of diagnostic methods and treatment of leishmaniasis at five university hospitals in Norway.

Material And Method: The number of cases, diagnosis and treatment of suspected leishmaniasis were registered prospectively in the period March 2014 - September 2017 at the university hospitals of Bergen, Oslo, Stavanger, Trondheim and Tromsø.

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Alveolar echinococcosis (AE) caused by the fox tapeworm Echinococcus multilocularis is a zoonosis presenting with focal liver lesions and has a poor prognosis without treatment. The disease is common in Central and Eastern Europe but has been highly unusual in Sweden. A suspicion of AE usually arises through radiology and the diagnosis may be confirmed by histology and/or serological antibody detection.

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is a parasite of human and nonhuman primates, other mammals, and birds. Due to overlapping morphological features, cysts of may be confused with those of other species commonly found in human fecal samples, including immature cysts of Although the presence of in human -positive stool samples may be rare, its prevalence is likely underestimated due to such confusion. Here, we give examples of diagnostic approaches applied so far and summarize data on the molecular epidemiology of , including host specificity and phylogeography.

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In May 2014, a cluster of Yersinia enterocolitica (YE) O9 infections was reported from a military base in northern Norway. Concurrently, an increase in YE infections in civilians was observed in the Norwegian Surveillance System for Communicable Diseases. We investigated to ascertain the extent of the outbreak and identify the source in order to implement control measures.

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Article Synopsis
  • The World Health Organization aimed to control fishborne zoonotic trematodes (FZT) in endemic areas by 2020 using preventive chemotherapy with praziquantel.
  • A study in Northern Vietnam followed 396 individuals, revealing a significant drop in trematode egg prevalence after treatment, but a concerning rise in reinfection rates within the first year.
  • The findings suggest that while preventive chemotherapy is helpful, addressing animal reservoirs and improving farm management are crucial for lasting control, advocating for a One Health approach that integrates human, animal, and environmental health.
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Reaching the goal of control, elimination and eradication of the Neglected Tropical Disease in a foreseeable future provides significant challenges at the ground level especially regarding helminthiasis. Helminths are still mainly diagnoses by egg identification in stool, methods with low sensitivity and for most species low specificity. Cross-sectoral collaboration with regard to zoonoses is almost non-existing and cross-validation by inter-laboratory evaluation of diagnostic tests is not a common practice.

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More sensitive methods for diagnosing infection with Schistosoma japonicum are needed as control becomes more effective. We compared a real-time polymerase chain reaction (PCR) for stool samples with conventional diagnostic methods in a study of 1,727 persons from Anhui Province, China. Seroprevalence determined by using an indirect hemagglutination assay (IHA) was much higher (26.

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Background: The endemic countries are in a diagnostic dilemma concerning Schistosoma japonicum with increasing difficulties in diagnosing the infected individuals. The formol-ethyl acetate sedimentation concentration technique is preferred by many clinical microbiology laboratories for the detection of parasites in stool samples. It is potentially more sensitive than the diagnostic methods traditionally used.

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The aim of this study was to validate a simplified high-dosage, extended-interval netilmicin dosage regimen for infants. A total of 129 infants receiving 163 treatment courses of netilmicin (6 mg kg every 24 or 36 h depending on gestational age (GA), postnatal age and postmenstrual age) was analysed. Serum netilmicin concentrations were monitored before (Cmin), 30 min (C0.

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