[Ciguatera fish poisoning while on vacation].

This case report presents a four-year-old Danish girl, who acquired ciguatera fish poisoning after eating a meal containing fish while being on vacation in Cuba. After returning to Denmark, her main complaint was pain in her lower legs and disrupted sleep. She was seen by her primary care physicians and at a paediatric department but was not diagnosed, until a specialist in tropical diseases saw her seven months after her return from Cuba.

Sources of circulating 3,5,3'-triiodothyronine in hyperthyroidism estimated after blocking of type 1 and type 2 iodothyronine deiodinases.

Context: Graves' hyperthyroidism and multinodular toxic goiter lead to high serum T(3) compared with serum T(4). The source of this high T(3) has not been clarified.

Objective: Our objective was to assess the role of iodothyronine deiodinase type 1 (D1) and type 2 (D2) for T(3) production and to estimate the sources of T(3) in hyperthyroidism.