Publications by authors named "Toraj Zamir-Nasta"
Article Synopsis
- Chronic alcohol consumption, particularly from beer, has adverse effects on male fertility, specifically impacting spermatogenesis and the expression of key proteins in testicular tissue.
- In a study with male mice, those consuming alcoholic beer showed increased p21 protein and gene expression, while cyclin D1 levels decreased, alongside signs of oxidative stress and testicular damage over time.
- The findings suggest that alcoholic beer disrupts testicular cell division, leading to decreased sperm production and quality, highlighting the negative effects of ethanol on male reproductive health.
Background And Purpose: Aflatoxins are highly toxic compounds that can cause acute and chronic toxicity in humans and animals. This study aimed to evaluate the expression of BDNF and GFAP, histopathological changes, and oxidative stress factors in brain tissue exposed to aflatoxin G1 (AFG1) in male rats.
Experimental Approach: Twenty-eight male Wistar rats were used.
Background And Purpose: Aflatoxin (AF) is a mycotoxin produced by various strains of the family. AFG1 as one of the most important types is highly found in cereals and grains. AF affects sperm production or even its quality.
View Article and Find Full Text PDFThis study was done in order to investigate time-dependent effect of AFB1 on expression of genes involving in cell cycle check point machinery at G, S, and M phases. For this purpose, 24 mature male Swiss albino mice were randomly divided into control and test groups. The animals in test group subdivided into three groups, which received the AFB1 at a daily dose of 20 µg/kg body weight, through intraperitoneal (i.
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