Publications by authors named "Topi Luoto"
Aim Of The Study: Continuous surgical developments, growing awareness of patient representatives and limited health-care resources are pushing for innovative approaches to ensure equal high-quality pediatric surgical care. We aimed to describe early experiences and assess surgical safety of a novel nationwide pediatric surgery collaborative initiative.
Methods: In 2021, general pediatric surgeons representing all five independent university hospitals performing neonatal surgery in Finland initiated national collaboration, the Finnish pediatric surgery hub (FPSH), for sharing of surgical expertise and collective learning.
Aim Of The Study: We aimed to evaluate disease characteristics, associated malformations and surgical outcomes of congenital intestinal atresia.
Methods: We identified all patients with jejunoileal (JIA) or colonic atresia (CA) treated at the Helsinki University Children's hospital during 1947-2019 and collected clinical data retrospectively from archived and electronic medical records.
Results: Of the 180 included patients, 156 had JIA and 24 CA.
Purpose: Various complications are associated with percutaneous endoscopic gastrostomy (PEG) procedures in children. The push technique is being increasingly used, but its complications are insufficiently characterized. We aimed to assess all complications related to PEG procedures and compare the safety of the pull and push techniques.
View Article and Find Full Text PDFArticle Synopsis
- **Study Overview**: The APPSYPP trial is a multicenter study investigating the effectiveness of appendectomy versus symptomatic treatment for children aged 7-16 with uncomplicated acute appendicitis confirmed by imaging.
- **Inclusion Criteria**: Participants must meet specific criteria including imaging-confirmed appendicitis, CRP levels ≤ 65 mg/l, and consent to either surgery or symptomatic management involving an initial hospital stay.
- **Primary Outcome**: The main goal is to assess treatment success within 30 days, defined by the absence of treatment failure, which varies for both surgical and symptomatic treatments.
Long-term Outcomes and Health Perceptions in Pediatric-onset Portal Hypertension Complicated by Varices.
J Pediatr Gastroenterol Nutr
May 2020
Objectives: Outcomes of pediatric-onset portal hypertension are poorly defined. We aimed to assess population-based long-term outcomes of pediatric-onset portal hypertension complicated by varices.
Methods: All children with esophageal varices (n = 126) were identified from 14,144 single nationwide referral center endoscopy reports during 1987 to 2013, and followed up through national health care and death registers.
Background: Splenectomy is performed frequently for various and primarily hematologic indications in children and adolescents. We analyzed the long-term outcome after splenectomy (median, 8.7 years) focusing on sepsis, portal vein thrombosis (PVT), and retained accessory spleen.
View Article and Find Full Text PDFBackground: Neonatal autosomal-recessive polycystic kidney disease (ARPKD) is associated with pulmonary hypoplasia and severe respiratory distress. There is no published information on long-term lung function in ARPKD survivors.
Methods: Pulmonary function tests, including spirometry and diffusion capacity, were performed in a nationwide cohort of Finnish paediatric patients with ARPKD.
Objectives: We correlated liver and kidney manifestations in a national cohort of patients with autosomal recessive polycystic kidney disease (ARPKD).
Methods: A total of 27 consecutive patients with ARPKD were included. Hepatobiliary disorders were comparatively evaluated in 2 groups: children in group 1 (n = 10) displayed renal failure as infants and those in group 2 (n = 17) had normal kidney function through the first year of life.
Background: The internal jugular vein is routinely used as a graft for the Rex shunt. We analyzed results of mesoportal bypass using an alternative autologous graft.
Methods: Twenty-one children with extrahepatic portal vein obstruction were treated with a Rex shunt constructed using both greater saphenous veins.