Management of the Patient with Aggressive and Resistant Papillary Thyroid Carcinoma.

Purpose: Papillary carcinoma is the most frequent type of thyroid cancer and was considered the most benign of all thyroid carcinomas, with a low risk of distant metastases. However, there are some variants of papillary thyroid carcinoma that have affinity to spread in many organs, such as: lymph nodes, lungs and bones.

Aim: The aim of this study was presentation of a case with papillary carcinoma of the thyroid gland, very persistent and resistant in treatment with I 131.

An experimental comparison of two different technetium source activities which can imitate thyroid scintigraphy in case of thyroid toxic nodule.

Purpose: In cases of thyroid toxic autonomous nodule, anterior projection of Tc-99m pertechnetate image shows a hot nodule that occupies most, or the entire thyroid lobe with near-total or total suppression of the contra lateral lobe. In this case is very difficult to distinguish toxic nodule from lobe agenesis. Our interest was to estimate and determinate the rate of radioactivity when the source with high activity can make total suppression of the second source with low activity in same conditions with thyroid scintigraphy procedures.

The importance of determining procalcitonin and C reactive protein in different stages of sepsis.

Rapid and early diagnosis of systemic infections is very important for acting on time with an adequate therapy. The aim of this study is to determine the diagnostic importance of procalcitonin (PCT) and C-reactive protein (CRP) of bacterial infections in different stages of sepsis.PCT and CRP have been determined in 45 newborns, 1-21 days of age, with different stages of sepsis, in the centre for prematurely born neonates.

Immunomodulating and antiviral therapy in herpes zoster.

Two groups of patients with herpes zoster were followed up. The first group was subjected, beside a symptomatic therapy, to an immunological and antiviral treatment. The control group was treated only symptomatically.

[Beneficial effects of immunostimulant and antiviral therapy of ophthalmic herpes zoster].

A group of 16 patients with ophthalmic zona zoster received antiviral and immunostimulative treatment with Romanian specific products. Results were spectacular. The problem of the identity of the varicella and zoster viruses is discussed.

[Immunochemical therapy of warts and growths due to papillomavirus].

A complex immuno-chemical treatment (immuno-stimulation, blockage of virus replication, interferon induction) was applied to 23 patients with warts and vegetations with various localisations. Results confirmed the treatment efficiency.

[The beneficial effects of immunostimulating and antiviral therapy on ophthalmic zona].

A group of 16 patients with ophthalmic zona zoster received antiviral and immunostimulating treatment with Romanian specific products. Results were spectacular. The problem of the identity of the varicella and zoster viruses is discussed.

[The immunochemical therapy of warts and growths due to the papillomavirus].

A complex immuno-chemical treatment (immuno-stimulation, blockage of virus replication, interferon induction) was applied to 23 patients with warts and vegetations with various localisations. Results confirmed the treatment efficiency.

Immunologic and antiviral therapy in herpetic keratitis.

A group of 113 patients with herpetic keratitis who were administered besides the classical therapy (local and general) immunologic and antiviral treatments was studied. The following Romanian non-toxic preparations were used: "SRE Immunostimulent", "Moroxidin" chlorhydrate and "Antiherpin". The control group including 120 patients received a classical treatment and the first signs of recovery appeared after 30 days; in 32% of the patients recurrences, were recorded during the first year.

[The efficacy of a combined therapy against herpes virus genital infections].

A complex immuno-chemical therapy (inhibition of viral replication, stimulation of cell mediated immunity, interferon induction) was applied to 75 patients with herpes virus genital infections. Treatment was followed by complete recovery in 66.7% of the subjects and by considerable reduction of relapse frequency and of pain in the others.

Laboratory diagnosis in a case of fatal progressive vaccinia due to manifest immunologic deficiencies.

A case of progressive vaccinia is described, in a 21 years old man, diagnosed after 8 months of vaccinial lesion's evolution. The area of vaccination developed progressive necrosis and metastatic lesions evolved on various regions of the body. The vaccinia virus was isolated on the chorioallantoic membrane of embryonated eggs, from the cutaneous lesions, blood, internal organs and even from the apparently intact skin.

The role of vaccinia virus in the evolution of some human hemopathies.

Six cases of severe hemopathy, detected following smallpox revaccination are described. Their onset was favoured by vaccinia virus-induced suppression of cell-mediated and humoral immunity. In two leukemia patients humoral immunity was present, but insufficient to assure protection of the diseased organisms, the outcome being fatal.

Dynamics of anti-vaccinia HAI antibodies during the first month after smallpox revaccination at 20 years.

Anti-vaccina HAI antibody titers were dynamically followed up and correlated with the type of cutaneous reaction in 91 small pox revaccines aged 20-21 years. Serum samples collected at 2-day intervals for 14 days and on day 30 post inoculation (p.i.