Publications by authors named "Topal I"

Article Synopsis
  • This study investigates the effectiveness of mesotherapy in managing chronic musculoskeletal pain following COVID-19 infection in 96 patients.
  • Two treatment groups were analyzed: one receiving oral medications (diclofenac potassium, thiocolchicoside, cyanocobalamin) and the other undergoing intradermal mesotherapy using lidocaine and cyanocobalamin.
  • Results showed that both treatments improved pain and neuropathic symptoms, but mesotherapy proved significantly more effective than oral therapy, with greater reductions in pain scores.
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BACKGROUND Type D personality has been associated with adverse clinical outcomes and poor quality of life in many diseases. This study aimed to evaluate the effects of type D personality on pain, anxiety and depression, sleep quality, and quality of life in 50 patients with fibromyalgia syndrome. MATERIAL AND METHODS Fifty patients with fibromyalgia and 50 healthy controls were included in the study.

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BACKGROUND Non-union of distal tibia fractures is a challenge in orthopedic surgery and can be due to open fractures, osteopenia, infection, or failure of surgical devices. This retrospective study aimed to describe 8 patients with non-union of distal tibial fractures treated with distal tibial nail and screw fixation. MATERIAL AND METHODS According to the Gustilo-Anderson classification, 3 patients had type 2 open fractures, 1 had a type 3 open fracture, 1 had a type 1 open fracture, and 3 had closed fractures.

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Objective: There is a worldwide increase in the incidence of malignant melanoma (MM). Although it is a highly aggressive tumor and associated with high mortality and morbidity rates, it is highly curable if diagnosed early. Both genetic and environmental risk factors are associated with MM, which may show geographic variations.

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Reconstructing network dynamics from data is crucial for predicting the changes in the dynamics of complex systems such as neuron networks; however, previous research has shown that the reconstruction is possible under strong constraints such as the need for lengthy data or small system size. Here, we present a recovery scheme blending theoretical model reduction and sparse recovery to identify the governing equations and the interactions of weakly coupled chaotic maps on complex networks, easing unrealistic constraints for real-world applications. Learning dynamics and connectivity lead to detecting critical transitions for parameter changes.

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Background: Preterm births cause fetuses to be born without completing the development of their organs. Due to this undesirable situation, it is the pulmonary tissue which has to be most exposed to harmful effects of extrauterine environment. Early disappearance of the prophylactic and constructive effects of amniotic fluid (AF) on developing tissues, such as pulmonary tissue, facilitates the formation of pulmonary morbidities resulting from oxygen.

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Background: Taxifolin (TXF) is a flavonoid found abundantly in citrus/onion. Encouraging results on its renoprotective effect have been reported in a limited number of drug-induced nephrotoxicity animal models. The present study aimed to evaluate for the first time the potential renoprotective effects of TXF in a paracetamol (PAR)-induced nephrotoxicity rat model.

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Introduction: Due to the chronic recurrent nature of psoriasis vulgaris (PV) and lack of definitive treatment for the disease, patients often resort to alternative treatments. Physicians seem to have low awareness of this issue.

Objectives: To elicit the perceptions of 1,621 PV patients on complementary and alternative medicine (CAM) and examine factors reported to worsen PV.

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Background: A broad spectrum of skin diseases, including hair and nails, can be directly or indirectly triggered by COVID-19. It is aimed to examine the type and frequency of hair and nail disorders after COVID-19 infection.

Methods: This is a multicenter study conducted on consecutive 2171 post-COVID-19 patients.

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Background: The new type of corona virus has a wide range of symptoms. Some people who have COVID-19 can experience long-term effects from their infection, known as post-COVID conditions. The authors aimed to investigate prolonged musculoskeletal pain as a symptom of the post-COVID-19 condition.

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Background: Demand for age determination by medical methods from legal authorities is of critical importance, especially for people in pubertal age. We planned this study to evaluate the potential utility of biochemical methods in these applications. We aim to investigate whether alkaline phosphatase (ALP), bone-specific alkaline phosphatase (BALP), and osteocalcine can be used in the determination of age.

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Objective: The World Health Organization emphasizes that it is essential that infants be fed only breast milk for the first six months. This study is designed to investigate the frequency of exclusive breastfeeding and the related factors during the first six months in infants born in 2016 in Erzincan province.

Materials And Methods: Our study is a cross-sectional study, and the study population consisted of 2166 babies born in 2016, and registered with the family physicians.

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The aim is to compare the markers of oxidative stress in iron deficient children to that of non-anemic children. Serum thiol-disulfide level, ferroxidase activity and ischemia-modified albumin (IMA) levels were compared between iron deficiency anemia (IDA) and non-anemic children. A total of 117 children, 66 with IDA and 51 non-anemic children were included in the study.

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Aim: Hyperbilirubinemia causes oxidative stress.

Method: We evaluated three oxidative stress markers in hyperbilirubinemic neonates (native/total thiol levels, serum ferroxidase activity and ischemia modified albumin (IMA), comparing these levels to levels in a control group to determine which indicators were the most sensitive.

Results: Serum from 124 term infants (67 with pathologic jaundice and 57 controls) were evaluated.

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Background: Impairment of thiol/disulfide homeostasis, as well as vitamin D deficiency, are responsible for the pathophysiology of many acute and chronic diseases. This study examined the relationship between thiol/disulfide homeostasis and vitamin D level and supplementation.

Methods: A total of 203 healthy children were included in the study.

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Objective: Cisplatin is an anticancer drug used for treating childhood solid tumors. Symptoms related to cisplatin-induced cardiovascular adverse effects may be mild or severe. Rutin (vitamin P1) has many properties, including as antioxidant, anticancer, antidiabetic, antimicrobial, antiulcer, and tissue renewal properties.

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Acute generalized exanthematous pustulosis is a rare drug-induced eruption that is characterized by acute, nonfollicular sterile pustules on an erythematous and edematous base. The most frequently implicated drugs are beta-lactam antibiotics. Hydroxychloroquine has been widely used to treat dermatologic and rheumatologic diseases and has been reported as a rare cause of acute generalized exanthematous pustulosis.

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Inducible urticaria is a heterogeneous subgroup of chronic urticarias caused by a wide variety of environmental stimuli, such as exercise, cold, heat, pressure, sunlight, vibration, and water. A new term, follicular traction urticaria, was suggested as an unusual form of inducible urticarias. We report a patient who was diagnosed with follicular traction urticaria.

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Background: Vitiligo is an acquired pigmentary skin disorder affecting 0.1-4% of the general population. The nails may be affected in patients with an autoimmune disease such as psoriasis, and in those with alopecia areata.

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