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Publications by authors named "Tooru Asano"

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ITPA gene variation and ribavirin-induced anemia in patients with genotype 2 chronic hepatitis C treated with sofosbuvir plus ribavirin.
Miyako Murakawa Yasuhiro Asahina Hiroko Nagata Mina Nakagawa Sei Kakinuma Yu Asano Tooru Asano

Hepatol Res

October 2017

Article Synopsis
  • This study focuses on how genetic variations in the ITPA gene affect the side effects and effectiveness of the Sofosbuvir and Ribavirin (SOF/RBV) treatment for genotype 2 chronic hepatitis C.
  • About 90 patients were analyzed, showing that those with certain ITPA gene variants (CA/AA) experienced less anemia and required fewer dose reductions of Ribavirin compared to those with the CC genotype.
  • Overall, the research suggests that understanding a patient's ITPA genotype could help predict their risk of anemia during treatment and improve the management of hepatitis C therapy.
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