Publications by authors named "Tonje Trulssen Hildre"

Article Synopsis
  • - Occupational asthma (OA) is categorized into allergic asthma and irritant-induced asthma, with the latter having three phenotypic subtypes.
  • - This study examined exhaled volatile organic compounds (VOCs) from individuals with OA and healthy healthcare workers to identify potential biomarkers that differentiate OA from healthy controls and its subtypes.
  • - 536 VOCs were found, with specific compounds like 1-hexadecanol and xylene showing significant levels and potential links to metabolic changes related to asthma, suggesting these VOCs could improve asthma diagnosis and indicate occupational exposure.
View Article and Find Full Text PDF

Fractional exhaled nitric oxide (FeNO) is a breath-related biomarker of eosinophilic asthma. The aim of this study was to investigate FeNO variations due to environmental or occupational exposures in respiratory healthy subjects. Overall, 14 hairdressers and 15 healthcare workers in Oslo were followed for 5 workdays.

View Article and Find Full Text PDF

This manuscript presents the results of an exploratory study on the relationships between NF-κB response through Toll-like receptor (TLR) activation by dust characterized by fungal spore concentrations and species diversity. Personal total dust samples were collected from Norwegian waste sorting plants and then characterized for fungal spores and fungal species diversity, as well as for other bioaerosol components, including endotoxins and actinobacteria. The ability of the dust to induce an NF-κB response by activating TLR2 and TLR4 was evaluated, as well as the relationship between such responses and quantifiable bioaerosol components.

View Article and Find Full Text PDF