Background: Vasculopathy underlies diabetic complications, with perivascular adipose tissue (PVAT) playing crucial roles in its development. However, the changes in the cellular composition and function of PVAT, including the specific cell subsets and mechanisms implicated in type 2 diabetes mellitus (T2DM) vasculopathy, remain unclear.
Methods: To address the above issues, we performed single-cell RNA sequencing on the stromal vascular fraction (SVF) of PVAT from normal and T2DM rats.
Unlabelled: Abdominal aortic aneurysm (AAA) is a large-vessel disease with high mortality, characterized by complex pathogenic mechanisms. Current therapeutic approaches remain insufficient to halt its progression. Fungi are important members of the gut microbiota.
View Article and Find Full Text PDFNumerous studies have demonstrated the pivotal roles of intestinal microbiota in many physiopathological processes through complex interactions with the host. As a unique period in a woman's lifespan, pregnancy is characterized by changes in hormones, immunity, and metabolism. The gut microbiota also changes during this period and plays a crucial role in maintaining a healthy pregnancy.
View Article and Find Full Text PDFIn this work, nanosized P-doped SnO (SnO-P) was prepared by a sol-gel method as a catalyst for the V/V redox reaction in vanadium redox flow battery. Compared with SnO, the electrochemical performance of SnO-P is significantly improved. This is because P doping provides more active sites and shows greatly improved electrical conductivity, thereby increasing the electron transfer rate.
View Article and Find Full Text PDFIn this study, a SnO-carbon nanotube (SnO-CNT) composite as a catalyst for vanadium redox flow battery (VRFB) was prepared using a sol-gel method. The effects of this composite on the electrochemical performance of /VO, and on the V/V redox reactions and VRFB performance were investigated. The SnO-CNT composite has better catalytic activity than pure SnO and CNT due to the synergistic catalysis of SnO and the CNT.
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