Publications by authors named "Tongxin Xiao"

Article Synopsis
  • The study investigates the unique clinical traits, treatments, and outcomes of pediatric-onset growth hormone-secreting pituitary adenoma (GHPA) patients compared to adults, aiming to enhance clinical strategies for these cases.
  • Findings reveal that pediatric patients, predominantly male, often experience earlier complications, have higher hormone levels, and face more surgical risks than adults, despite similar cure rates.
  • Both groups show a comparable recurrence rate, but pediatric patients are more prone to hypopituitarism, while adult patients have a higher incidence of other tumors, highlighting the need for tailored treatment approaches.
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Background: Growth hormone (GH) positive pituitary neuroendocrine tumors do not always cause acromegaly. Approximately one-third of GH-positive pituitary tumors are classified as non-functioning pituitary tumors in clinical practice. They typically have GH and serum insulin-like growth factor 1 (IGF-1) levels in the reference range and no acromegaly-like symptoms.

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Article Synopsis
  • This study looked at how often people with acromegaly, a condition caused by too much growth hormone, get cancers compared to others.
  • They found that people with acromegaly had a higher chance of getting certain cancers, especially thyroid cancer and colorectal cancer.
  • It suggests that doctors should keep a closer eye on these patients for cancer, especially if they have high levels of growth hormone and IGF-1 after treatment.
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(1) Background: Pituicytomas are rare gliomas located in the neurohypophysis or infundibulum. A misdiagnosis of pituicytoma as pituitary adenoma is common because of similar location and occasional endocrine disturbances. (2) Case presentation: We present two cases with the comorbidity of pituicytoma and Cushing's disease (CD).

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