Publications by authors named "Tongxin Wei"
Article Synopsis
- Achieving a high piezoelectric coefficient with stable temperature performance in lead-free piezoceramics is challenging due to their sensitivity to temperature changes.
- * The study demonstrates a method to improve both piezoelectric coefficient and thermal stability through atomic-scale design of ferroelectric structures, achieving a coefficient of ~430 pC/N with only ~7% fluctuation from room temperature to 100 °C.
- * Further optimization using annealing techniques enhances stability up to 150 °C with a coefficient of ~380 pC/N, matching the stability of traditional lead-based piezoceramics.
Article Synopsis
- Curcumin, a compound with anti-inflammatory and anti-tumor effects from traditional Chinese medicine, struggles with issues like low stability and poor absorption, which is why N-acetyl-L-cysteine (NAC) was added to enhance its absorption in the body.
- The study involved grinding curcumin with NAC using a method called airflow pulverization and analyzing the mixture for structural changes, finding no significant alteration in the crystal forms or dissolution rates.
- After administering the mixture intranasally, high concentrations of curcumin were detected in the plasma and specific brain regions over different time intervals, suggesting a quicker and more efficient absorption route for curcumin into the brain.
Curcumin attracted attention due to its promising anti-cancer properties and safety performance. However, its poor aqueous solubility and low bioavailability have to be overcome before it goes into clinic use. Here, porous composite particles are prepared by loading curcumin into mesoporous material SBA-15, and its therapeutic effect on lung cancer via inhalation administration have also been evaluated.
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