A Nomogram Predicting Recurrence and Guiding Adjuvant Radiation for Thymic Carcinoma After Resection.

Background: Resection is an effective treatment for thymic carcinoma. We aimed to develop a nomogram for postoperative prediction of recurrence-free survival for patients with thymic carcinoma and guide adjuvant radiotherapy.

Methods: A total of 198 patients who underwent surgery were divided into training cohort (n = 152) and validation cohort (n = 46).

Clinical and pathology analysis of 1 case of adult pleural pulmonary blastoma: A case report.

Rationale: Pulmonary blastoma is a rare primary lung cancer that can be categorized into adult type and child type. The clinical symptoms and imaging features of pulmonary blastoma are nonspecific, making it difficult to diagnose preoperatively. Postoperative pathology with immunohistochemical staining can help diagnosis.

Differential expression of miR-21 and miR-75 in esophageal carcinoma patients and its clinical implication.

In Xinjiang, China, esophageal carcinoma has a high incidence in Kazak and Uighur populations. MicroRNA (miR)-21 and miR-375 are related to esophageal carcinoma. This study thus investigated their potencials in early diagnosis and prognosis in Kazak and Uighur populations, to provide evidences for serum markers of esophageal cancer.

Real-time polymerase chain reaction for the diagnosis of necrotizing herpes stromal keratitis.

Aim: To design, optimize and validate a rapid, internally controlled real-time polymerase chain reaction (RT-PCR) test for herpes simplex virus (HSV) in the diagnosis of necrotizing herpes stromal keratitis.

Methods: Tears alone or together with corneal epithelium scrapings from 30 patients (30 eyes) suspected of necrotizing herpes stromal keratitis were tested for HSV DNA by RT-PCR. The samples were collected during the first visit and then on the subsequent 7, 14, 28, 42, and 56d.

Haemoglobin A₁c measurement in patients with chronic kidney disease.

Objectives: The aim of this study is to investigate the interference of carbamylated haemoglobin (cHb) to haemoglobin A1c (HbA₁c) measurements in patients with chronic kidney disease (CKD) by three ion-exchange chromatography methods.

Design And Methods: We included three ion-exchange chromatography methods (Bio-Rad Variant II, G7 and HA-8160) and one affinity chromatography method (Primus Ultra2) to test HbA₁c. In vitro carbamylation of haemoglobin was also performed to test interference of carbamylation.

Effect of exenatide on inflammatory and oxidative stress markers in patients with type 2 diabetes mellitus.

Aim: This study was designed to determine the effect of exenatide on inflammatory and oxidative stress markers in type 2 diabetes mellitus (T2DM) patients who were suboptimally controlled with metformin and/or sulfonylurea.

Subjects And Methods: Twenty-three patients with T2DM with inadequate glucose control were randomly divided into two groups: exenatide group (E group) (12 patients, 5 μg b.d.

Mouse thymus targeted peptide isolated by in vivo phage display can inhibit bioactivity of thymus output in vivo.

Heterogeneity of the vasculature in different organs has been well documented by the method of in vivo phage display. Using this technology, several peptide ligands that home to tissue-specific vascular endothelial cell have been isolated. Such peptide ligands directed against specific vascular surface molecules can be used as targeted therapeutic compounds or imaging agents to the vasculature of the specific organ in vivo.