Publications by authors named "Tongwha Kim"
Highly sensitive paper-based immunoassay using photothermal laser speckle imaging.
Biosens Bioelectron
October 2018
Article Synopsis
- - The paper discusses a new type of lateral-flow assay (LFA) that uses photothermal laser speckle imaging (PT-LSI) to improve sensitivity for detecting disease biomarkers compared to traditional LFAs, which often struggle with low detection limits.
- - This innovative sensor utilizes gold nanoparticles that generate heat when exposed to light, altering the membrane's optical properties to enhance detection of biomarker complexes.
- - Experimental results show that this new method can detect biomarkers 68-125 times better than conventional colorimetric detection methods, and its effectiveness is confirmed using FDA-approved kits for cryptococcal antigens.