Expression and Predictive Significance of FHL1 and SLIT3 in Surgically Resected Lung Adenocarcinoma.

Objective: Lung adenocarcinoma (LUAD) is the most common type of lung cancer. However, predictive biomarkers for early efficacy and prognosis evaluation in patients with surgically resected LUAD are not completely explained.

Methods: Differentially expressed genes (DEGs), gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were identified by RNA sequencing (RNA-Seq) between thirteen LUAD tissues and five normal lung tissues.

Coupled topological edge states in one-dimensional all-dielectric heterostructures.

We theoretically propose a coupled-topological-edge-state waveguide (CTESW), which is composed of stacked binary one-dimensional (1D) photonic crystals with opposite topological properties. The CTESW modes originate from the coupling between a sequence of topological edge states (TESs), which can be verified by the coupled mode theory (CMT). Based on finite element method (FEM), the tunable multiple transmission peaks due to CTESW modes are obtained, and the optical properties of the system can be modulated by the geometric parameters.

Enhanced Formaldehyde Oxidation Performance of the Mesoporous TiO(B)-Supported Pt Catalyst: The Role of Hydroxyls.

As one of the crystal phases of titania, TiO(B) was first utilized as a catalyst carrier for the oxidation of formaldehyde (HCHO). The mesoporous TiO(B) loaded with Pt nanoparticles enhanced the HCHO oxidation reaction whose reaction rate was 4.5-8.

Upregulated UCA1 contributes to oxaliplatin resistance of hepatocellular carcinoma through inhibition of miR-138-5p and activation of AKT/mTOR signaling pathway.

Hepatocellular carcinoma (HCC) inevitably developed oxaliplatin (OXA) resistance after long-term treatment, but the mechanism remains unclear. Here, we found that LncRNA UCA1 was upregulated in most of OXA-resistant HCC tissues and cells (HepG2/OXA and SMMC-7721/OXA). Follow-up analysis and online Kaplan-Meier Plotter revealed that HCC patients with high UCA1 level had a shorter survival compared with those with low expression.

Identification of a novel therapeutic candidate, NRK, in primary cancer-associated fibroblasts of lung adenocarcinoma microenvironment.

Purpose: Lung adenocarcinoma (LUAD) accounts for approximately half of patients in lung cancer. Cancer-associated fibroblasts (CAFs) are the major component in the tumor microenvironment (TME). Targeting CAFs is a promising therapeutic strategy for cancer treatment.

A novel metastatic promoter CEMIP and its downstream molecular targets and signaling pathway of cellular migration and invasion in SCLC cells based on proteome analysis.

Purpose: Metastasis is an unavoidable event happened among almost all small cell lung cancer (SCLC) patients. However, the molecular driven factors have not been elucidated. Recently, a novel hydrolase called cell migration inducing hyaluronidase (CEMIP) triggered both migration and invasion in many tumors but not SCLC.

Tunable multifunctional reflection polarizer based on a graphene metasurface.

Herein, we present a tunable multifunctional reflection polarizer, based on a graphene metasurface, which is composed of an array of cross double-ellipse graphene patches. A dual band of linear-to-linear (LTL) polarization conversions is achieved due to the superimposition of the two reflection components with a near 0° or 180° phase difference, in the mid-infrared region. By carefully choosing the parameters, linear-to-circular polarization conversion and broadband of LTL polarization conversion (about 0.

[Effects of paclobutrazol on the yield, quality, and related enzyme activities of different quality type peanut cultivars].

Selecting high-protein peanut cultivar KB008, high-fat cultivar Hual7, and high O/L cultivar Nongda818 as test materials, a field experiment was conducted in 2011 and 2012 to study the effects of foliar spraying paclobutrazol (PBZ) at late flowering stage on the kernel yield and quality and the activities of leaf carbon and nitrogen metabolism enzymes of the cultivars. Spraying PBZ increased the pod yield of the cultivars significantly via increasing the pod number per plant, decreasing the pod number per kilogram, and increasing the percentage of double kernel. Spraying PBZ also increased the kernel fat and soluble sugar contents but decreased the kernel protein content to varying degrees, and increased the O/L ratio of high-fat cultivar Hual7 significantly.