Advances in single ice crystal shaping materials: From nature to synthesis and applications in cryopreservation.

Antifreeze (glyco) proteins [AF(G)Ps], which are widely present in various extreme microorganisms, can control the formation and growth of ice crystals. Given the significance of cryogenic technology in biomedicine, climate science, electronic energy, and other fields of research, scientists are quite interested in the development and synthesis high-efficiency bionic antifreeze protein materials, particularly to reproduce their dynamic ice shaping (DIS) characteristics. Single ice crystal shaping materials, a promising class of ice-controlling materials, can alter the morphology and growth rate of ice crystals at low temperatures.

A step-by-step strategy to design active and stable quaternary intermetallic compounds for the hydrogen evolution reaction.

Multinary intermetallic compounds with rich chemical compositions enable one to achieve a logical design for desired materials based on the required function. In this work, we have demonstrated a step-by-step strategy to design a quaternary intermetallic compound that exhibits highly active and stable performance for the hydrogen evolution reaction (HER). With binary intermetallic TaCo as the starting point, the minor inclusion of a ductile Cu element in TaCo to form ternary TaCuCo can substantially lower the degradation rate from 20% to 5% after sintering treatment (, enhance connectivity between particles).

Balance between Activity and Stability of Single Metal and Intermetallic Compounds for Electrocatalytic Hydrogen Evolution Reaction.

The higher population of the antibonding state around the Fermi level will result in better activity yet lower stability of HER (Re vs Ru metal). There seems to be a limitation or balance for using a single metal since the bonding scheme of a single metal is relatively simple. Combining Re (strong bonding), Ru (HER active), and Zr metal (corrosion-resistant) grants ternary intermetallic compound ZrReRu, exhibiting excellent HER activity and stability in acidic and alkaline electrolytes.

All-Day Anti-Icing/Deicing Film Based on Combined Photo-Electro-Thermal Conversion.

Solar energy-facilitated icephobic films have emerged as clean and renewable materials, which can potentially solve energy loss problems during anti-icing/deicing applications. However, there is a significant challenge for all-day and continuous anti-icing/deicing applications under practical conditions with insufficient sunlight or no sunlight. In this work, a chemical oxidation polymerization method was used to prepare in situ self-wrinkling porous poly(dimethylsiloxane) (PDMS)/polypyrrole (PPy) (POP-P) films based on a facile sugar template method.

MALAT1 knockdown inhibits prostate cancer progression by regulating miR-140/BIRC6 axis.

Background: Prostate cancer (PCa) is the second most common cancer among men globally. Long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been reported to be implicated in tumorigenesis and progression of PCa. However, the pathogenesis of MALAT1 in PCa has not been thoroughly elaborated.

Long noncoding RNA GAS5 modulates α-Solanine-induced radiosensitivity by negatively regulating miR-18a in human prostate cancer cells.

Radiotherapy is an adjuvant treatment of surgery in prostate cancer, while radioresistance has been the challenge of treatment. It has been reported that α-Solanine exhibits anti-cancer activity and enhances the chemo- and radio-sensitivity in several human cancers, whereas the role of α-Solanine on radiosensitivity to PCa remains to be uncovered yet. We found α-Solanine decreased cell viability in human PCa cells rather than normal prostate epithelial cells in vitro.

[Over-expression of miR-151a-3p inhibits proliferation and migration of PC-3 prostate cancer cells].

Objective To observe the effect of microRNA-151a-3p (miR-151a-3p) up-regulation on the proliferation and migration of prostate cancer cells and explore the possible molecular mechanism. Methods The expression of miR-151a-3p in PC-3M, C4-2B, 22RV1, DU-145, PC-3, LNCap human prostate cancer cells and RWPE-1 human normal prostate epithelial cells was detected by real-time fluorescence quantitative PCR. PC-3 cells with the lowest expression of miR-151a-3p were used for subsequent experiments.

Clinical comparison of the efficiency and security of balloon dilators versus fascial dilators in percutaneous nephrolithotripsy (PCNL).

Objective: To compare the efficiency and security of the balloon dilators versus fascial dilators in percutaneous nephrolithotripsy (PCNL), We compared the difference of intraoperative and postoperative parameters of patients using these two different methods of expansion and having no significant statistic differences in peroperative parameters.

Methods: This is a retrospective analysis of 134 patients undergoing PCNL with upper urinary calculi from January 2012 to January 2014 in Luoyang Central Hospital affiliated to Zhengzhou University. These patients meeting the inclusion criteria were divided into two groups: the group of balloon dilators (group A) and the group of fascial dilators (group B).

MiR-192 suppresses the tumorigenicity of prostate cancer cells by targeting and inhibiting nin one binding protein.

Nin one binding (NOB1) protein has been identified as an oncogene in various human cancers, including prostate cancer. MicroRNAs (miRs) have also been recognized as novel regulatory molecules of gene expression. The present study aimed to discover potential miRs that target NOB1 and regulate NOB1 expression in prostate cancer.