DMT1 Maintains Iron Homeostasis to Regulate Mitochondrial Function in Porcine Oocytes.

Iron plays critical roles in many cellular functions, including energy production, metabolism, and cell proliferation. However, the role of iron in maintaining oocyte quality remains unclear. In this study, DMT1 was identified as a key iron transporter during porcine oocyte maturation.

Deep learning Radiomics Based on Two-Dimensional Ultrasound for Predicting the Efficacy of Neoadjuvant Chemotherapy in Breast Cancer.

We investigate the predictive value of a comprehensive model based on preoperative ultrasound radiomics, deep learning, and clinical features for pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) for the breast cancer. We enrolled 155 patients with pathologically confirmed breast cancer who underwent NAC. The patients were randomly divided into the training set and the validation set in the ratio of 7:3.

Multimodal data integration using machine learning to predict the risk of clear cell renal cancer metastasis: a retrospective multicentre study.

Purpose: To develop and validate a predictive combined model for metastasis in patients with clear cell renal cell carcinoma (ccRCC) by integrating multimodal data.

Materials And Methods: In this retrospective study, the clinical and imaging data (CT and ultrasound) of patients with ccRCC confirmed by pathology from three tertiary hospitals in different regions were collected from January 2013 to January 2023. We developed three models, including a clinical model, a radiomics model, and a combined model.

Preparation of a magnetic phosphazene-based hyper crosslinked polymer for the fast and efficient extraction of chlorophenols from water and peach juice.

Two magnetic phosphazene-based hyper crosslinked polymers (M-HCP-OP-TMC and M-HCP-OP-TCL) were newly synthesized by the reaction of Friedel-Crafts acylation, and the M-HCP-OP-TMC showed an excellent extraction capability and rapid adsorption kinetics for chlorophenols as an adsorbent. Then, an efficient analytical method was built for the preconcentration and quantification of chlorophenols from water and peach juice samples by combining M-HCP-OP-TMC based magnetic solid-phase extraction (MSPE) with HPLC-UV detection. The linear response range for the chlorophenols by the method was 0.

A core-shell structured magnetic sulfonated covalent organic framework for the extraction of benzoylureas insecticides from water, pear juice and honey samples.

Three magnetic covalent organic frameworks (named M-TpPa-SONa, M-TpPa-SOH and M-TpPa) were prepared by the solvothermal synthesis method with 1,3,5-trimethylphenol (TP) and either 2-sulfo-1,4-phenylenediamine (Pa-SOH) or p-phenylenediamine (Pa) as monomers. Among them, the M-TpPa-SONa possessed relatively high hydrophilicity, good magnetic responsiveness, and high affinity for the benzoylureas (BUs) insecticides. It was then explored as the magnetic solid-phase extraction adsorbent for the extraction of six BUs (diflubenzuron, triflumuron, hexaflumuron, teflubenzuron, flufenoxuron and chlorfluazuron) from water, pear juice and honey samples prior to high-performance liquid chromatography with ultraviolet detection.