Case report: Acute ST-elevation myocardial infarction and cardiogenic shock caused by a giant right sinus of Valsalva aneurysm and right coronary artery compression.

A sinus of Valsalva aneurysm (SVA) is a rare aortic disease that may be congenital or acquired. Patients with an intact SVA are usually asymptomatic, whereas a ruptured SVA may cause acute chest pain and dyspnea. We present a rare case of acute ST-elevation myocardial infarction and cardiogenic shock in a 51-year-old man.

Review on Functional Testing Scenario Library Generation for Connected and Automated Vehicles.

The advancement of autonomous driving technology has had a significant impact on both transportation networks and people's lives. Connected and automated vehicles as well as the surrounding driving environment are increasingly exchanging information. The traditional open road test or closed field test, which has large costs, lengthy durations, and few diverse test scenarios, cannot satisfy the autonomous driving system's need for reliable and safe testing.

Joint effects of serum ferritin and body mass index on the risk of coronary artery disease: a case-control study.

Objectives: Serum ferritin and body mass index (BMI) have been reportedly associated with coronary artery disease (CAD) risk. The aim of the present study was to explore the interaction between serum ferritin and BMI on CAD risk.

Design: Hospital-based case-control study.

Association of serum ferritin with coronary artery disease.

Background: Published results regarding the association of serum ferritin with coronary artery disease (CAD) were conflicting, thus a case-control study and a meta-analysis were performed to assess the association between serum ferritin and CAD risk.

Methods: A hospital-based case-control study was conducted with 258 CAD cases and 282 healthy controls. The restricted cubic spline (RCS) function with three knots was used to assess the concentration-risk association between serum ferritin and CAD risk.

Fibroblast growth factor receptor 4 polymorphisms and coronary artery disease: a case control study.

Fibroblast growth factors (FGFs) and their receptors (FGFRs) play important roles in vascular system. FGFR4 rs351855 (Gly388Arg) polymorphism has shown to be a risk factor for many diseases. The aim of this study was to investigate the association between FGFR4 polymorphisms and the susceptibility to coronary artery disease (CAD) in the Chinese population.

Association of total iron binding capacity with coronary artery disease.

Objective: A case-control study and a meta-analysis were conducted to assess the association between total iron binding capacity (TIBC) and coronary artery disease (CAD) risk.

Methods: A hospital-based case-control study was conducted with 258 CAD cases and 282 healthy controls. Logistic regression was utilized to estimate odds ratio (OR) with 95% confidence interval (CI) and adjust potential confounders.

Association of nicotinamide adenine dinucleotide phosphate oxidase p22phox gene 549C>T polymorphism with coronary artery disease.

Background: The p22phox is a critical component of the superoxide-generating vascular nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. Several polymorphisms in p22phox gene are studied for their association with cardiovascular diseases. However, no publication is available to assess the relation of 549C > T polymorphism in p22phox gene to coronary artery disease (CAD) risk.

Association of C47T polymorphism in SOD2 gene with coronary artery disease: a case-control study and a meta-analysis.

Oxidative damage promotes atherosclerosis. SOD2 is an important antioxidant enzyme. A case-control study and a meta-analysis were performed to assess the association of C47T polymorphism in SOD2 gene with premature, late-onset and overall coronary artery disease (CAD) risk.

Joint effects of eNOS gene T-786C and ADH2 Arg47His polymorphisms on the risk of premature coronary artery disease.

Introduction: Both T-786C mutation in endothelial nitric oxide synthase (eNOS) gene and alcohol dehydrogenase (ADH) gene polymorphism such as ADH3 gamma1/gamma2 have been reportedly associated with coronary artery disease (CAD). Since ADH2 Arg47His polymorphism is common in Asian population, the aim of this present study was to assess the interaction between eNOS gene T-786C and ADH2 Arg47His polymorphisms on premature CAD risk.

Materials And Methods: Hospital-based case-control study was conducted with 167 premature CAD and 235 late-onset CAD patients.

Facilitated PCI in younger Chinese patients with AMI.

Presently, facilitated percutaneous coronary intervention (PCI) in patients remains controversial. We evaluated the efficacy and safety of facilitated PCI, intravenous low-dose rt-PA administration prior to urgent PCI, in Chinese patients < 70 years of age with ST-segment elevation myocardial infarction. Our results suggest that the age and dosage of thrombolytics should be noticed seriously when considering facilitated PCI.

[Association between G894T mutation in endothelial nitric oxide synthase gene and premature coronary heart disease].

Objective: To assess the association between G894T (Glu298Asp) mutation in exon 7 of the endothelial nitric oxide synthase gene and premature coronary heart disease (P-CHD).

Methods: Hospital-based case-control study was conducted. Newly-diagnosed CHD patients were recruited as study subjects.

The T1128C polymorphism of neuropeptide Y gene in a chinese population.

Background: Several papers have shown that the T1128C polymorphism of the neuropeptide Y (NPY) gene was related to certain diseases and disorders. However, the allele frequency of the 1128C showed significant differences among some populations with different genetic backgrounds, being absent in Japanese and Korean populations. Therefore, this present study was aimed to explore whether the T1128C polymorphism of the NPY gene exists in a Chinese population.