Colonic leiomyosarcoma with lung metastasis or lung cancer: A case report.

Colonic leiomyosarcoma is a tumor with a very low incidence and a high metastasis rate, mainly lung metastasis. This report provides insights into the future treatment. Thoracic puncture is necessary for patients with pulmonary nodules.

Integrated profiling identifies DXS253E as a potential prognostic marker in colorectal cancer.

Background: Increasing evidence suggests that DXS253E is critical for cancer development and progression, but the function and potential mechanism of DXS253E in colorectal cancer (CRC) remain largely unknown. In this study, we evaluated the clinical significance and explored the underlying mechanism of DXS253E in CRC.

Methods: DXS253E expression in cancer tissues was investigated using the Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases.