Publications by authors named "Tonghan Yang"

Ternary intermetallic compounds RMnGe with complex magnetic phase transitions are expected to be developed and applied in spintronic storage and computing devices in the future. The relationship between the crystal structure and physical properties (electrical conductivity, thermal analysis, and complex magnetic transformation) of ErMnCoGe ( = 0-1.45) alloys was studied in the range of 80-600 K.

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Implementing novel oral drug delivery systems with controlled drug release behavior is valuable in cancer therapy. Herein, a green synthetic approach based on the sol-gel technique was adopted to prepare MgFeO nanoparticles at different calcination temperatures using citric acid as a chelating/combustion agent. In this context, pH-responsive and magnetic carboxymethyl starch/alginate hydrogel beads (CMCS-SA) containing the MgFeO nanoparticles were developed as potential drug carriers for the anticancer drug (Doxorubicin, Dox) release in simulated gastrointestinal fluids.

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Considerable concern exists regarding water contamination by various pollutants, such as conventional pollutants (e.g., heavy metals and organics) and emerging micropollutants (e.

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In this experiment, a series of MnCoGeLa (x = 0, 0.01, 0.03) alloy samples were prepared using a vacuum arc melting method.

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In this study, carboxymethyl cassava starch (CMCS)-functionalized magnetic nanoparticles (CMCS@FeO) were synthesized via a simple one-pot co-precipitation method using CMCS materials with varying degrees of substitution, and used for the adsorption/removal of doxorubicin hydrochloride (Dox; a clinically available anti-cancer drug) from aqueous solution. The adsorption of Dox was studied using experimental conditions with varied pH, temperature, initial Dox concentration, and CMCS@FeO dosage. The CMCS@FeO adsorbents were characterized by scanning electron microscopy, transmission electron microscopy, infrared spectroscopy, X-ray diffraction, thermogravimetric analysis, and vibrating sample magnetometry.

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The phase relationships of the ternary Co-Ni-In system at 673 K and 873 K were investigated by means of powder X-ray diffraction, scanning electron microscopy equipped with energy dispersive spectroscopy, and optical microscopy. Though CoIn does not exist at 873 K, the ternary solid solution CoNiIn exists at both 673 K and 873 K with different composition ranges. The Rietveld refinements were carried out to investigate the crystal structure of CoNiIn (x = 0.

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The aim of the present study was to identify miRNAs that were differentially expressed in hepatocellular carcinoma (HCC) by comparing normal and cancer tissue samples and to analyze the correlation of the target genes and HCC. The gene expression profile of GSE31383 was downloaded from the Gene Expression Omnibus database, including 19 samples, 9 normal and 10 from HCC tissue samples. The differentially‑expressed miRNAs were identified with packages in R language and further analyzed using bioinformatics methods.

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Background: A total of 2%-2.9% of the population in China is infected with hepatitis C virus (HCV). This study estimated the prevalence and incidence of HCV among Chinese blood donors.

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Background: It is important to understand donor return behavior to maintain sufficient numbers of blood donors in developing countries where blood supplies are often inadequate.

Study Design And Methods: A total of 54,267 whole blood (WB) donors who donated between January 1 and March 31, 2008, at the five blood centers in China were followed for 2.5 years.

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Background: Information regarding the risk factors for human immunodeficiency virus (HIV) infection among Chinese donors is important for understanding the trend of HIV transmission routes and for developing effective donor behavioral screening policies.

Study Design And Methods: In 2009 to 2011, a total of 77 HIV-positive and 649 HIV-negative consented donors who screened nonreactive for hepatitis B virus, hepatitis C virus, syphilis, and alanine aminotransferase in four Retrovirus Epidemiology Donor Study-II Chinese regions received and completed a questionnaire by mail regarding their recent and past medical procedures, drug use, and sexual behaviors, etc. Exploratory and confirmatory factor analyses grouped questions into three risk factors.

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Article Synopsis
  • This study examined the genetic variability of the hepatitis B virus (HBV) in blood donors from China, focusing on genotypes and mutations in the S region of the virus.
  • Out of 245 HBsAg-positive blood samples, 93% were successfully genotyped, revealing that genotypes B and C were the most common, with B/adw being the predominant strain.
  • The presence of mutations in the major hydrophilic region (MHR) of the S region in some samples raises concerns about transfusion safety, as these mutations could lead to failures in immunization and HBsAg detection.
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Background: The global human immunodeficiency virus (HIV)-1 epidemic is becoming increasingly diverse and complex. Molecular epidemiologic characteristics were studied for HIV-1-infected blood donors from five Chinese regions to determine genotype diversity and drug resistance mutations (DRMs) profile.

Study Design And Methods: HIV-1 confirmed-reactive serum samples were collected from 172 blood donors from five blood centers during 2007 to 2010.

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Background/aims: The aim of this study was to investigate the relationship between a new tumor-relative protein (BC047440) expression and clinic pathological parameters of hepatocellular carcinoma (HCC), and to evaluate the prognostic value of BC047440 for HCC patients.

Methods: Following the prokaryotic expression and polyclonal antibodies generation of BC047440, two methods, including western blot and immunohistochemical staining were employed to detect BC047440 expression in 68 HCC specimens. The correlation between BC047440 expression and clinicopathologic outcome, and prognostic value of BC047440 for HCC patients were analyzed.

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Objective: Surgical separation of the fused liver is extremely risky and sometimes life-threatening in conjoined twins because of the potential risks of hypovolemia and hemorrhagic shock.

Methods: Three pairs of symmetrical conjoined twins sharing fused livers were successfully separated by using a simple but effective local blockade measure without disturbing the portal circulation.

Results: The volume of intraoperative blood loss was minimal, and no major complications occurred.

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Background: In China recruitment and retention of sufficient numbers of safe blood donors continues to be a challenge. Understanding who donates blood, particularly those who donate larger (>200 mL) whole blood (WB) units, will help blood centers to target more effective recruitment and retention strategies.

Study Design And Methods: Demographic characteristics of 226,489 allogeneic WB donors from January to December 2008 at five geographically and ethnically diverse, urban blood centers were analyzed.

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Objective: Screening and identification of differentially expressed genes in human primary hepatocellular carcinoma(HCC).

Methods: The differentially expressed genes subtracted cDNA library of HCC constructed by suppression subtractive hybridization(SSH) technique was screened by colony in situ hybridization, then the positive clones were further screened with PCR amplification. The positive clones were sequenced and analyzed for homology in the Genbank databases with Basic Local Alignment Search Tool BLAST .

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