Publications by authors named "Tong-Yi Men"

Background: The number and survival rate of simultaneous liver-kidney transplant (SLKT) recipients have increased dramatically since 2002. However, the long-term effectiveness of SLKT in patients with hepatitis B is unknown.

Material/methods: Forty-six patients who visited the Organ Transplant Center of the Shanghai First People's Hospital between January 2001 and May 2005 had hepatitis B virus infection and renal failure (any degree), and underwent organ transplantation: 21 patients underwent SLKT and 25 patients underwent liver transplant (LT) alone.

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Article Synopsis
  • A study compared low-dose and high-dose rATG induction therapy to a control group in kidney transplant recipients to find an optimal balance between effectiveness and complications from 2009 to 2012.
  • Results showed that both low-dose and high-dose rATG groups had lower acute rejection rates compared to the control group, although the long-term survival rates and early renal function recovery were similar across all groups.
  • The high-dose rATG group experienced more cases of CMV infections and thrombocytopenia, suggesting low-dose rATG may be a better option for renal transplantation.
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Hepatic hemangioma patients with Kasabach-Merritt syndrome have reportedly been cured by liver transplantation. However, liver transplantation as a potential cure for a stable patient without Kasabach-Merritt syndrome remains debatable. We report the case of a 27-year-old female patient with a giant hepatic hemangioma.

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Prostate cancer is a big killer in many regions especially American men, and this year, the diagnosed rate rises rapidly. We aimed to find the biomarker or any changing in prostate cancer patients. With the development of next generation sequencing, much genomic alteration has been found.

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The hepatic growth factor hepatopoietin Cn (HPPCn) prevents liver injury induced by carbon tetrachloride in rats. Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid produced by sphingosine kinase (SphK). S1P and S1P receptors (S1PRs) are involved in liver fibrogenesis and oxidative injury.

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Article Synopsis
  • Liver transplantation (LT) is an effective treatment for end-stage liver diseases, but infections from multi-drug resistant Gram-negative bacilli (MDR-GNB) are becoming more common among recipients, especially shortly after the procedure.
  • These MDR-GNB infections are now a leading cause of mortality post-LT, with factors such as the severity of underlying diseases and acute rejection contributing to the risk.
  • To reduce the incidence of these infections, improvements in LT techniques, careful management of antibiotics and immunosuppressants, and better understanding of risk factors are necessary for enhancing patient outcomes.
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Objectives: Gram-negative bacilli infections, especially multidrug-resistant gram-negative bacilli infections, are the leading cause of high mortality after liver transplantation. This study sought to investigate the type of infection, infection rate, pathogenic spectrum, antibiotic-resistance profile, risk factors, and epidemiology of multidrug-resistant gram-negative bacterial infection.

Methods: A retrospective cohort study was conducted and data of 217 liver transplant patients receiving cadaveric livers between January 2007 and April 2010 were analyzed.

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