Publications by authors named "Tomu Ichinohe"

Article Synopsis
  • This study evaluates how different vertebral distraction-fusion techniques affect adjoining cervical vertebrae in dogs, specifically the C5-C6 and C4-C5 segments.
  • Ten Beagle cervical vertebrae were tested using three stabilization methods (intact, titanium plate, and PMMA), with biomechanical assessments measuring range of motion (ROM) during various movements.
  • Results indicated that both fusion techniques altered the mechanical behavior at adjacent vertebrae, with significant variations in ROM based on the method used, which suggests potential for adjacent segment disorders.
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Hydroxyapatite (HA)/poly-l-lactide(PLLA) composite biomaterials are available for orthopedic applications, but bioresorption and cell-mediated inflammation in bone cortex are unknown. We conducted an 84-month follow-up study with Beagle dogs that were subjected to implants with either PLLA (left femur) or HA/PLLA (right femur). Histological and radiographic analysis showed that HA/PLLA screws induced significant increases in HA content from 36 months onward and complete burr hole closure at 60 months, whereas PLLA screws did not.

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