Publications by authors named "Tomoyuki Yoshiyama"
Background: Peritumoral edema (PE) identified on T2-weighted breast MRI is a factor for poor prognosis in breast cancer.
Purpose: To assess the prognostic value of residual PE (rPE) in patients with PE positive breast cancer prior to neoadjuvant chemotherapy (NACT) who subsequently underwent curative surgery.
Study Type: Retrospective.
Background: CA15-3 is often elevated in breast cancer recurrence and rarely in ductal carcinoma in situ (DCIS). We report a case of DCIS with elevated CA15-3 levels, which was diagnosed after over 2 years of follow-up.
Case Presentation: A 74-year-old woman presented with a left-sided breast mass and pain.
[Prognostic Value of Basal Marker Expression in Early Stage Breast Cancer].
Gan To Kagaku Ryoho
February 2020
The expression of basal marker could be a significant factor for poor prognosis in early stage breast cancer. We evaluated the prognostic value of basal marker in each breast cancer subtype. According to immunohistochemistry assay, CK5/6-posi- tive and/or EGFR-positive was defined as basal marker-positive.
View Article and Find Full Text PDFArticle Synopsis
- Metastatic breast cancer (MBC) is typically deemed incurable, focusing treatment on extending life and improving quality of life rather than curing the disease.
- Newer therapeutic agents have improved patient prognoses and raised questions about the potential for curing MBC.
- Key challenges in answering these questions stem from short follow-up periods in clinical trials and the cancer cells' resistance to common treatments, although new therapies like HER2-targeted agents and PARP-1 inhibitors show promise.