Publications by authors named "Tomoyuki Noyama"
Introduction: The aim of this study was to clarify the safety and efficacy of breath-hold irradiation in liver stereotactic body radiotherapy (SBRT).
Methods: A retrospective analysis was conducted on 57 consecutive patients who received SBRT for hepatocellular carcinoma or liver metastases between 2013 and 2021. Breath-hold irradiation was implemented for patients treated after April 2020.
Article Synopsis
- A study analyzed survival outcomes for stage I non-small cell lung cancer (NSCLC) patients who received either surgery or stereotactic body radiotherapy (SBRT) between 2012 and 2016.
- Of the 538 patients, those who had surgery experienced better overall survival rates (90.1% at 3 years) compared to those treated with SBRT (70.5% at 3 years), although cancer-specific survival was similar between both groups.
- The results indicate that while surgery is associated with higher overall survival, the differences in cancer-specific survival prompt the need for further research comparing these treatments in a more controlled manner.
Background Breathing motion management is the key to delivering stereotactic body radiation therapy (SBRT) for liver lesions. This study aimed to compare the dosimetric parameters of liver SBRT using two different techniques: free breathing and breath hold. Method The study included 11 patients with liver metastases or hepatocellular carcinoma who underwent liver-directed SBRT.
View Article and Find Full Text PDFBackground/aim: The aim of this study was to identify prognostic factors for brain metastases treated with Gamma knife radiosurgery.
Patients And Methods: Multivariate Cox proportional hazards regression analyses were conducted for patients who received treatment between June 2013 and March 2018.
Results: A total of 131 consecutive patients were included.
Reduced expression of microRNA122 (miR122), a liver-specific microRNA, is frequent in hepatocellular carcinoma (HCC). However, its biological significances remain poorly understood. Because deregulated amino acid levels in cancers can affect their biological behavior, we determined the amino acid levels in miR122-silenced mouse liver tissues, in which intracellular arginine levels were significantly increased.
View Article and Find Full Text PDF