Carbon dioxide uptake in a eutrophic stratified reservoir: Freshwater carbon sequestration potential.

Carbon capture and storage due to photosynthesis activities has been proposed as a carbon sink to mitigate climate change. To enhance such mitigation, previous studies have shown that freshwater lakes should be included in the carbon sink, since they may capture as much carbon as coastal areas. In eutrophic freshwater lakes, there is uncertainty about whether the equilibrium equation can estimate the partial pressure of carbon dioxide (pCO), owing to the presence of photosynthesis due to phytoplankton, and pH measurement error in freshwater fluid.

Palbociclib regulates intracellular lipids in mammary tumor cells by secreting lipoprotein lipase.

Background: Lipoprotein metabolism is essential for the growth and proliferation of cancer cells, and is involved in the supply of energy and cellular components. Lipoprotein lipase (LPL) is a very important enzyme in lipoprotein metabolism; however, the details underlying the mechanism of LPL secretion are unclear. Palbociclib is an antitumor drug that inhibits cell cycle progression and suppresses the growth of cancer cells.

β-Estradiol Enhanced Secretion of Lipoprotein Lipase from Mouse Mammary Tumor FM3A Cells.

The role of β-estradiol (E) in lipoprotein metabolism in mammary tumors is unclear, therefore, we investigated the effect of E on the secretion of lipoprotein lipase (LPL) from mouse mammary tumor FM3A cells. E-treated cells increased the secretion of active LPL from FM3A cells in a time- and dose-dependent manner. Activity of mitogen-activated protein kinase (MAPK) was increased in the tumor cells treated with E, and enhanced secretion of LPL was suppressed by MAPK kinase 1/2 inhibitor, PD98059, extracellular signal-regulated kinase (ERK) 1/2 inhibitor, FR180204, p38 MAPK inhibitor, SB202190, and phosphatidyl inositol 3-kinase (PI3K) inhibitor, LY294002.