Publications by authors named "Tomoya Maruyama"
Article Synopsis
- Researchers have developed synthetic droplets that mimic droplets formed via liquid-liquid phase separation (LLPS) in living cells, which hold potential for applications in artificial cells and molecular robotics.
- This study showcases a method for controlling the timing of DNA-based LLPS droplets, enabling precise division through timed chemical triggers.
- The ability to control the release order of these triggers allows for a multistep droplet division process, which can be applied to molecular computing for tasks like comparing microRNA concentrations.
Background: Proton pump inhibitors (PPIs) are reported to decrease the efficacy of immune checkpoint inhibitors (ICIs), but there are few reports on the association between ICI efficacy and antacids other than PPIs, and simultaneous examination of the effects of antacids, corticosteroids, and non-steroidal anti-inflammatory drugs (NSAIDs) on ICI therapy.
Methods: We conducted a retrospective study of 381 patients with non-small cell lung cancer who received ICI therapy from January 1, 2016 to December 31, 2022. The primary endpoint was overall survival (OS) and the secondary endpoint was progression-free survival (PFS).
A case of angioimmunoblastic T-cell lymphoma presenting with migration of lung shadows.
Respir Med Case Rep
December 2023
A 62-year-old woman presented with chronic cough. Chest CT showed multiple nodules and consolidation. Bronchoscopy could not confirm a specific diagnosis.
View Article and Find Full Text PDFAn 80-year-old woman who developed allergic bronchopulmonary aspergillosis (ABPA) was admitted to our institution in 2023 for an enlarged pulmonary mass lesion. She had developed ABPA in 2017, and corticosteroid therapy had improved the mucoid impaction of the bronchi. Because part of the lesion remained, increased doses of corticosteroid, antifungals, and biologics were administered, but the pulmonary lesion enlarged in 2022.
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