Publications by authors named "Tomoya Hirose"
Article Synopsis
- - The study focuses on Hereditary Angioedema (HAE), a rare genetic condition causing swelling, with a significantly lower identification rate in Japan compared to the expected prevalence, highlighting a gap in diagnosis.
- - Researchers developed an AI model to identify suspected HAE patients using medical histories from the US and validated the model's performance with Japanese data, achieving better-than-expected precision in identifying HAE cases.
- - The AI model demonstrated a sensitivity score of 61.5% in the US dataset and 37.6% in the Japanese dataset, successfully predicting patients with typical HAE symptoms, indicating its potential utility in clinical settings.
Article Synopsis
- The study investigates how pre-existing medical conditions affect the outcomes of elderly trauma patients in Japan, focusing on in-hospital mortality.
- Using data from the Japan Trauma Data Bank, researchers analyzed 19,598 patients and identified several medical conditions linked to higher mortality rates.
- Key findings revealed that moderate or severe liver disease had the strongest association with in-hospital mortality (AOR: 7.087), followed by multiple malignancies and congestive heart failure, indicating that these conditions pose significant risks for elderly trauma patients.
Isolated traumatic spinal cord injury (t-SCI) and traumatic brain injury (TBI) represent significant public health concerns, resulting in long-term disabilities and necessitating sophisticated care, particularly when occurring concurrently. The impact of these combined injuries, while crucial in trauma management, on clinical, socioeconomic, and health care outcomes is largely unknown. To address this gap, our secondary retrospective cohort study used data from the Japan Trauma Data Bank, covering patients enrolled over a 13-year period (2006-2018), to elucidate the effects of concurrent t-SCI and TBI on in-hospital mortality.
View Article and Find Full Text PDFArticle Synopsis
- Emergency medical systems faced challenges in hospital acceptance for COVID-19 patients, highlighted by the concept of "difficulty in hospital acceptance" (DIH), which is a key performance metric in Japan.
- A retrospective study involving over a million patients identified 3.8% who experienced DIH, revealing that factors like low oxygen levels, elevated body temperature, and specific COVID-19 waves significantly influenced DIH rates.
- The study underlined that critical health indicators, particularly during the fourth wave of the pandemic, were pivotal in determining patients' acceptance into medical facilities.
Background: The novel corona virus (COVID-19) pandemic occurred worldwide. Although an excessive burden was placed on emergency medical institutions treating urgent and severe patients, its impact on patient outcome remains unknown. This study aimed to assess the impact of the COVID-19 pandemic in 2021 on the emergency medical services (EMS) system and patient outcomes in Osaka Prefecture, Japan.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to analyze trends in severe road traffic injuries among children in Japan and identify factors leading to in-hospital mortality from 2004 to 2018.
- Out of 4,706 hospitalized child patients, common injury causes included bicycle crashes (34.4%), pedestrian accidents (28.3%), and motorcycle crashes (21.3%), with an overall in-hospital mortality rate of 11.2%.
- Key findings indicated decreasing rates of motorcycle crashes and in-hospital mortality, while factors like vehicle type, specific injuries, and time period significantly influenced mortality risk, highlighting the need for improved child road safety measures.
Article Synopsis
- The study aimed to examine how the COVID-19 pandemic influenced ambulance transports for self-harm in Japan from 2018 to 2021, focusing on identifying vulnerable age groups.
- Researchers used a comprehensive database from the Osaka Prefectural Government, analyzing ambulance transports for self-harm among 10,843 patients, primarily women with a median age of 38.
- Results showed a slight increase in the incidence rate over the years, but no significant change in the overall incidence or 21-day mortality due to self-harm was found, although there was an 11.7% increase in the 20-29 age group in 2020.
Purpose: Computed tomography (CT) has become essential for the management of trauma patients. However, appropriate timing of CT acquisition remains undetermined. The purpose of this study was to assess the relationship between time to CT acquisition and mortality among adult patients with severe trauma.
View Article and Find Full Text PDFBovine leukemia virus (BLV) has spread worldwide and causes serious problems in the cattle industry owing to the lack of effective treatments and vaccines. Bovine leukemia virus is transmitted via horizontal and vertical infection, and cattle with high BLV proviral load (PVL), which is a useful index for estimating disease progression and transmission risk, are considered major infectious sources within herds. The PVL strongly correlates with highly polymorphic bovine lymphocyte antigen (BoLA)-DRB3 alleles.
View Article and Find Full Text PDFAim: The impact of the coronavirus disease (COVID-19) pandemic on the emergency medical service system in Japan has not been fully revealed. The purpose of this study was to determine the impact of the COVID-19 pandemic in 2021 on the difficulty in hospital acceptance of patients and patient outcome in Osaka Prefecture.
Methods: This study was a descriptive epidemiological study with a 3-year study period from January 2019 to December 2021.
Background: Little is known about the transport and outcomes of emergency patients with cardiocerebrovascular diseases in Japan before and during the COVID-19 pandemic.
Methods and results: Data were extracted from a population-based registry in Osaka, Japan, from 2019 to 2021. There were almost no differences in the numbers of emergency patients hospitalized with myocardial infarction, stroke, or heart failure or their deaths.
This prospective observational single-center cohort study aimed to determine an association between cerebrovascular autoregulation (CVAR) and outcomes in hypoxic-ischemic brain injury post-cardiac arrest (CA), and assessed 100 consecutive post-CA patients in Japan between June 2017 and May 2020 who experienced a return of spontaneous circulation. Continuous monitoring was performed for 96 h to determine CVAR presence. A moving Pearson correlation coefficient was calculated from the mean arterial pressure and cerebral regional oxygen saturation.
View Article and Find Full Text PDFIntroduction: Methemoglobinemia is a condition in which methemoglobin is increased and the oxygen carrying capacity of tissues is decreased, causing a lack of oxygen to the whole body. RNA (ribonucleic acid) sequencing technologies have made it possible to systematically examine how the human transcriptome responds to invasive pathologies. To our knowledge, no previous studies have reported the results of RNA sequencing in a patient with methemoglobinemia.
View Article and Find Full Text PDFThe purpose of this study was to describe the characteristics of published international literature using the Japan Trauma Data Bank (JTDB). We undertook a scoping review of studies using data from JTDB. We carried out a systematic search of the following databases on November 21, 2022, using search terms that covers trauma registries in Japan: MEDLINE, Web of Science, CINAHL, and Cochrane Library.
View Article and Find Full Text PDFAim: The nationwide impact of the coronavirus disease (COVID-19) pandemic on major trauma in Japan is unknown. The nationwide registry-based data of the Japanese Trauma Data Bank were analyzed to elucidate the impact of COVID-19 on the epidemiology, treatment, and outcomes of major trauma patients.
Methods: Among patients transported directly from the injury site by ambulance with an Injury Severity Score of ≥16, we compared patients managed from April to December in 2019 to those managed from April to December in 2020.
Purpose: Understanding epidemiological patterns in patients with severe sports-related injuries between children and adults is important for injury prevention. We ought to describe the characteristics and outcomes of patients with severe sports-related injuries and compare the characteristics between children and adults.
Methods: We conducted a retrospective analysis of the Japan Trauma Data Bank (JTDB).
Background: Large-scale data on cranial nerve injuries are scarce. Methods: This study enrolled 361,706 patients registered in the Japanese Trauma Data Bank from 2004 to 2018. We selected patients with cranial nerve injury using the corresponding Abbreviated Injury Scale codes and examined the incidence and characteristics.
View Article and Find Full Text PDFThe lack of established diagnostic criteria makes diagnosing blunt cardiac injury difficult. We investigated the factors associated with blunt cardiac injury using the Japan Trauma Data Bank (JTDB) in a multicenter observational study of blunt trauma patients conducted between 2004 and 2018. The primary outcome was the incidence of blunt cardiac/pericardial injury.
View Article and Find Full Text PDFBackground: Blunt traumatic diaphragmatic rupture (TDR) is a rare condition that is seen in patients with blunt thoracoabdominal trauma. However, factors that are associated with blunt TDR have not been fully revealed. The purpose of this study was to evaluate the factors that are associated with blunt TDR in trauma patients with a chest or abdominal injury using nationwide trauma registry data in Japan.
View Article and Find Full Text PDFObjectives: The spread of COVID-19 has affected the incidence of other infectious diseases, but there are no reports of studies using comprehensive regional population-based data to evaluate the impact of COVID-19 on influenza incidence. We attempted to evaluate the impact of COVID-19 on influenza using the population-based ORION (Osaka Emergency Information Research Intelligent Operation Network) registry.
Methods: The ORION registry of emergency patients treated by emergency medical service (EMS) personnel was developed by the Osaka Prefecture government.
Background: Early surveillance to prevent the spread of influenza is a major public health concern. If there is an association of influenza epidemics with mobile app data, it may be possible to forecast influenza earlier and more easily.
Objective: We aimed to assess the relationship between seasonal influenza and the frequency of mobile app use among children in Osaka Prefecture, Japan.
Objectives: This study aimed to examine the difference in mortality from serious road traffic injuries during the National Traffic Safety Campaign compared with other periods and identify the common mechanisms of injury by age group in Japan.
Design: A retrospective review of Japan Trauma Data Bank (JTDB).
Setting: A total of 280 participating major emergency institutions across Japan.
Aim: To assess relationships between abdominal angiography and outcomes in adults with blunt liver injuries.
Methods: A retrospective observational study carried out from January 2004 to December 2018. Adult blunt-trauma patients with AAST grade Ⅲ-Ⅴ were analyzed with in-hospital mortality as the primary outcome using propensity-score-(PS) matching to seek associations with abdominal angiography findings.
Purpose: Sex-based differences in post-traumatic mortality have been widely discussed for quite some time. We hypothesized that age-related pathophysiologic changes would affect sex-based differences in post-traumatic mortality and aimed to verify the hypothesis using a nationwide trauma registry in Japan.
Methods: This was a retrospective analysis of trauma patients registered in The Japanese Trauma Data Bank.