Effects of Candidalysin Derived from on the Expression of Pro-Inflammatory Mediators in Human Gingival Fibroblasts.

() is frequently detected in the peri-implant sulcus with peri-implantitis, a major postoperative complication after oral implant therapy. However, the involvement of in the pathogenesis of peri-implantitis remains unclear. In this study, we aimed to clarify prevalence in the peri-implant sulcus and investigated the effects of candidalysin (Clys), a toxin produced by , on human gingival fibroblasts (HGFs).

Diagnosis of inflammatory peri-implant diseases using an immunochromatographic assay for calprotectin in peri-implant crevicular fluid.

Background: The incidence rate of peri-implant diseases is increasing with implant placement. Early detection of peri-implant diseases is important to prevent and treat these diseases, and a simple and objective diagnostic method is expected. Immunochromatographic (IC) assays are used for rapid diagnostic methods for some diseases.

Does Periodontal Tactile Input Uniquely Increase Cerebral Blood Flow in the Prefrontal Cortex?

We previously studied the effect of peripheral sensory information from sensory periodontal ligament receptors on prefrontal cortex (PFC) activity. In the dental field, an alternative dental implant without periodontal sensation can be applied for missing teeth. In this study, we examine whether periodontal tactile input could increase cerebral blood flow (CBF) in the PFC against elderly patients with dental implants lacking periodontal tactile (implant group), elderly individuals with natural teeth (elderly group), and young individuals with natural teeth (young group).

Calprotectin and cross-linked N-telopeptides of type I collagen levels in crevicular fluid from implant sites with peri-implant diseases: a pilot study.

Background: Peri-implant crevicular fluid (PICF) contains calprotectin and NTx, which are markers for inflammation and bone resorption, respectively. The aims of this pilot study were to compare calprotectin and NTx levels in PICF from implant sites with or without peri-implant diseases and to evaluate the usefulness of calprotectin and NTx as diagnostic markers for peri-implant diseases.

Methods: Thirty-five patients with dental implants participated in this pilot study.

Antifungal and Mechanical Properties of Tissue Conditioner Containing Plant-Derived Component: An In Vitro Study.

Purpose: To evaluate the antifungal activity and mechanical properties of a novel antifungal tissue conditioner containing Juncus powder.

Materials And Methods: Juncus powder was mixed with GC tissue conditioner at concentrations of 2.5%, 5.

Application of porous titanium in prosthesis production using a moldless process: Evaluation of physical and mechanical properties with various particle sizes, shapes, and mixing ratios.

The prosthetic applications of titanium have been challenging because titanium does not possess suitable properties for the conventional casting method using the lost wax technique. We have developed a production method for biomedical application of porous titanium using a moldless process. This study aimed to evaluate the physical and mechanical properties of porous titanium using various particle sizes, shapes, and mixing ratio of titanium powder to wax binder for use in prosthesis production.

Bone ingrowth of various porous titanium scaffolds produced by a moldless and space holder technique: an in vivo study in rabbits.

Porous titanium has long been desired as a bone substitute material because of its ability to reduce the stress shielding in supporting bone. In order to achieve the various pore structures, we have evolved a moldless process combined with a space holder technique to fabricate porous titanium. This study aims to evaluate which pore size is most suitable for bone regeneration using our process.

Digital assessment of preliminary impression accuracy for edentulous jaws: Comparisons of 3-dimensional surfaces between study and working casts.

Purpose: The aim of this study was to compare 3-dimensional surfaces of study and working casts for edentulous jaws and to evaluate the accuracy of preliminary impressions with a view to the future application of digital dentistry for edentulous jaws.

Methods: Forty edentulous volunteers were serially recruited. Nine dentists took preliminary and final impressions in a routine clinical work-up.

MiR-494-3p induced by compressive force inhibits cell proliferation in MC3T3-E1 cells.

Mechanical stimuli regulate fundamental cell processes such as proliferation, differentiation, and morphogenesis. We attempted to identify microRNA (miRNA) whose expression is changed during compressive treatment in MC3T3-E1, a pre-osteoblastic cell line. Microarray analysis followed by reverse transcription-quantitative polymerase chain reaction revealed that compressive force at 294 Pa for 24 h in MC3T3-E1 cells increased levels of miR-494-3p, miR-146a-5p, miR-210-3p, and miR-1247-3p.

Do sensation differences exist between dental implants and natural teeth?: a meta-analysis.

Objective: The purpose of this systematic review was to survey evidence pertaining to the sensation differences between natural teeth and osseointegrated dental implants.

Material And Methods: Using the MEDLINE (online PubMed) database, Cochrane Library, and Scientific Citation index, we performed a systematic search of articles. We used the following search terms: "perception or sensation and dental implant.

Influence of matrix attachment installation load on movement and resultant forces in implant overdentures.

Purpose: This in vitro study investigated the effect of attachment installation conditions on the load transfer and denture movements of implant overdentures, and aims to clarify the differences among the three types of attachments, namely ball, Locator, and magnet attachments.

Materials And Methods: Three types of attachments, namely ball, Locator, and magnetic attachments were used. An acrylic resin mandibular edentulous model with two implants placed in the bilateral canine regions and removable overdenture were prepared.

Blue-violet laser modification of titania treated titanium: antibacterial and osteo-inductive effects.

Background: Many studies on surface modifications of titanium have been performed in an attempt to accelerate osseointegration. Recently, anatase titanium dioxide has been found to act as a photocatalyst that expresses antibiotic properties and exhibits hydrophilicity after ultraviolet exposure. A blue-violet semiconductor laser (BV-LD) has been developed as near-ultraviolet light.

Oral factors affecting titanium elution and corrosion: an in vitro study using simulated body fluid.

Objectives: Ti, which is biocompatible and resistant to corrosion, is widely used for dental implants, particularly in patients allergic to other materials. However, numerous studies have reported on Ti allergy and the in vitro corrosion of Ti. This study investigated the conditions that promote the elution of Ti ions from Ti implants.

Formability and mechanical properties of porous titanium produced by a moldless process.

Tailor-made porous titanium implants show great promise in both orthopedic and dental applications. However, traditional powder metallurgical processes require a high-cost mold, making them economically unviable for producing unique devices. In this study, a mixture of titanium powder and an inlay wax binder was developed for moldless forming and sintering.

Telescopic magnetic attachment for implant-supported denture: evaluation of splint effect.

Purpose: Retrievability, connecting strength, and ease of laboratory work are important but conflicting prerequisites for the success of an implant superstructure, particularly with regard to immediate function. To resolve this issue, a telescopic magnetic attachment system has been developed for implant-supported removable dentures. The splinting effect of the attachment was evaluated for stress distribution and elevation with an in vitro model of three implants in an edentulous mandible.

Survival of immediate implant restoration: a retrospective study through 9-year-observation.

Purpose: The purpose of this retrospective study was to assess the implant survival rate and the risk factors associated with implant failure in patients who had undergone immediate implant restoration.

Materials And Methods: We performed a retrospective review and an outcome assessment of all patients who received immediate implant restoration between 2000 and 2010 in our department at Tokushima University Hospital. The patients were divided into groups on the basis of the predictor variables: age, gender, implant location, and number of implants per jaw.

New glass polyalkenoate temporary cement for cement-retained implant restoration: evaluation of elevation and retentive strength.

The purpose of this study was to evaluate four luting agents for cement-retained implant restorations in two aspects: post-cementation elevation of the superstructure and the retentive strength before and after thermocycling and mechanical cycling. The four evaluated luting agents were: new glass polyalkenoate hard-type (GH) and soft-type (GS) cements, polycarboxylate hard-type (HH) and soft-type (HS) cements. Elevation and retentive strength were measured using a CCD laser displacement sensor and a universal testing machine respectively.

A new method to prevent the corrosion of dental metals, during disinfection using functional water: sacrificial protection.

Purpose: This paper demonstrates a simple method using sacrificial protection for preventing the corrosion of dental metals.

Methods: Dental metals are directly connected or/and wound with a pure commercial aluminum/zinc wire/plate with high ionization tendency, before their immersion into oxidizing functional water.

Conclusion: Dental materials such as Co-Cr alloy wires, stainless steel, and Au-Ag-Pd alloys did not corrode when this method was used.

Implant prostheses and adjacent tooth migration: preliminary retrospective survey using 3-dimensional occlusal analysis.

Occlusal force analysis was retrospectively evaluated to clarify the proximal contact loss after fixed implant prosthesis placement. Twenty-eight patients (55 prostheses) with fixed implant prostheses in the posterior region were divided into 2 groups: proximal contact loss and unchanged groups. The occlusal force and its distribution were 3-dimensionally measured using the Dental Prescale system.

A new retrieval system for cement-retained implant superstructures: a technical report.

This article discusses two methods for improving the retrievability of cement-retained implant superstructures. One method involves incorporating a removal screw in the superstructure and the second method uses a small dimple on the abutment, accessed through a vent in the superstructure.

Formation of a lamellar compound by reaction of acrylic acid crystallosolvated in highly crystalline beta-chitin.

A lamellar compound resulted from reaction of acrylic acid inside crystalline beta-chitin and the structure was investigated. Beta-chitin acts like a layered crystal, having stacked molecular sheets composed of parallel chains bound in one direction by intermolecular amide hydrogen bonding. Small guest molecules can be inserted between the molecular sheets, and a crystallosolvate can be formed.

[A case of dental implant treatment with sinus lift for the maxillary molar sites].

Patient: Implant treatment with sinus lift was conducted in a 53-year-old male patient who had bilateral edentulous posterior maxilla with a limited bone volume of the sinus floor. One year later, the mobility at the anterior teeth of the maxilla increased and then decreased due to occlusal adjustment. The left posterior teeth of the mandible were extracted due to severe periodontitis and two implants were placed.

Immediate implant-supported oral rehabilitation using a photocurable plastic skull model and laser welding. A technical note on the screw-retained type: Part 1.

Purpose: This article describes a new procedure for immediate implant-supported oral rehabilitation using a photocurable resin skull model and a laser-welding apparatus.

Materials And Methods: Preoperatively, the framework was fabricated on a photocurable resin skull model produced from a CT scan and individually designed guide template. The implants were immediately placed using the guide template; laser welding connected the components of framework.

Dynamics of bone marrow pressure with tapping of titanium and hydroxyapatite implants in rabbits.

The purpose of the present study was to evaluate the difference in stress transfer between titanium (Ti) and hydroxyapatite (HA) by the measurement of bone marrow pressure using a catheter pressure transducer. Ti and HA implants were inserted in the tibiae of rabbits. A hole of 1 mm in diameter was drilled in the bone and a fine catheter pressure transducer was placed in the bone marrow through a tube.

Bone changes around hydroxyapatite and titanium implants after abutment placement in rabbits-observations using histological and three-dimensional examinations.

We have previously developed a computer-aided system for examination of the three-dimensional bone structure around implants and observed the bone changes in the healing period after implant placement. This paper describes the bone changes around hydroxyapatite (HA) and titanium (Ti) implants after abutment placement using histological and three-dimensional examinations. Twenty-four HA and Ti implants were embedded in the tibias of adult male New Zealand white rabbits.