Clinical features of hematological disorders caused by copper deficiency during long-term enteral nutrition.

Objective: Copper deficiency has been reported to cause hematological disorders. However, its clinical and hematological characteristics are not fully understood. Therefore, we investigated bedridden patients suffering from copper deficiency and tried to clarify the clinical features of hematological disorders caused by this condition.

Halothane modulates NMDA and non-NMDA excitatory synaptic transmission in rat cortical neurons.

Purpose: Although general anesthetics may decrease neuronal excitation, their detailed effects on spontaneous excitatory postsynaptic currents (EPSCs) remain controversial. We investigated and compared the effects of halothane on N-methyl-D-asparate (NMDA) and non-NMDA receptor-mediated postsynaptic currents.

Methods: Spontaneous synaptic currents were recorded by the patch clamp technique in cultured rat cortical neurons.