Publications by authors named "Tomoko Asada"
Introduction: Staphylococcus aureus bacteremia (SAB), especially when caused by methicillin-resistant S. aureus (MRSA), is of considerable clinical importance. In recent years, the proportion of MRSA among S.
View Article and Find Full Text PDFOsteogenesis imperfecta (OI) is a rare genetic disorder characterized by brittle bones. In this case report, we describe a patient who suffered from OI type XIV with a novel splice site variant in the TMEM38B gene. Further research is needed to better understand the relationship between the phenotype of OI type XIV and this variant.
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- Carbapenemase-producing bacteria are posing a significant global health threat, with unique geographic differences in their resistance genes observed.
- In a study conducted in Japan, researchers analyzed 104 bacterial isolates, identifying two main types of carbapenemase enzymes (IMP-1 and IMP-6) and noting that most showed low resistance to certain carbapenems but high resistance to penicillin and cephalosporins.
- The study highlights the presence of hypervirulent strains and transferable resistance genes, emphasizing the urgent need for monitoring and strategies to combat the rising threat of drug-resistant infections.
Article Synopsis
- CPT II deficiency is a common mitochondrial fatty acid oxidation disorder that often goes undetected in newborn screenings due to unreliable diagnostic indices.
- In a case involving a 7-month-old boy, researchers successfully diagnosed the condition by analyzing a dried blood specimen using new indices, leading to the identification of multiple affected newborns.
- Genetic analysis revealed a variety of alleles linked to the disease, with one variant (c.1148T>A) being the most common among the studied families.
The purpose of this study was to investigate the effect of L-citrulline ingestion on ECG QT interval. To accomplish this purpose, nine male subjects (age: 23.4±0.
View Article and Find Full Text PDFEnzymatic conversion of atmospheric aldehydes into alcohol in a phospholipid polymer film.
ACS Appl Mater Interfaces
February 2009
We developed a unique method for converting atmospheric aldehyde into alcohol using formaldehyde dehydrogenase from Pseudomonas putida (PFDH) doped in a polymer film. A film of poly(2-methacryloyloxyethylphosphorylcholine-co-n-butyl methacrylate) (PMB), which has a chemical structure similar to that of a biological membrane, was employed for its biocompatibility. A water-incorporated polymer film entrapping PFDH and its cofactor NAD(+) was obtained by drying a buffered solution of PMB, PFDH, and NAD(+).
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