Synopsis of recent research by authors named "Tomoki Imaoka"
- Tomoki Imaoka's research primarily investigates the optimization of drug delivery and efficacy, with a specific focus on developing new pharmacological compounds, such as the potent pyrido-pyridazinone derivatives that inhibit FER tyrosine kinase, aimed at improving antitumor activity and bioavailability.
- His work also emphasizes the importance of in vitro models for studying drug absorption and metabolism, particularly in the gastrointestinal tract, to better predict oral drug disposition and enhance therapeutic outcomes.
- Additionally, Imaoka explores renal interactions between drugs to understand their pharmacokinetics better, utilizing advanced microphysiological systems to simulate human organ functions and predict systemic drug behavior in conditions like chronic kidney disease.
