Publications by authors named "Tomohiro Tanemoto"
Article Synopsis
- The study focused on identifying pregnant women at risk for postpartum depression (PDS) using the Edinburgh Postnatal Depression Scale (EPDS) during different trimesters and shortly after giving birth.
- It involved following 129 healthy pregnant women throughout their pregnancy and evaluating their EPDS scores to determine the best time for screening and the effectiveness of different cutoff scores.
- Results showed the second trimester screening with a cutoff score of 4/5 had the highest predictive value for PDS, particularly among women with a family history of mental illness.
Article Synopsis
- A study was conducted to understand why some noninvasive prenatal tests (NIPT) yield nonreportable results by looking at maternal characteristics and related details.
- Out of 34,626 pregnant women tested, 110 (0.32%) had nonreportable cfDNA results, primarily due to low fetal fraction or altered genomic profiles.
- The research highlights the importance of classifying nonreportable results to offer clearer information and lessen anxiety for expecting mothers.
Article Synopsis
- - The study aimed to evaluate how fetal fractions in non-invasive prenatal testing (NIPT) can help predict pregnancy complications like gestational diabetes and hypertension by comparing results from different gestational ages and maternal characteristics.
- - Conducted as a multicenter cohort study, it analyzed data from 5,582 women with negative NIPT results to explore the links between fetal fractions and pregnancy outcomes such as miscarriages and complications.
- - Results indicated that women who developed hypertensive disorders tended to have lower fetal fractions early in pregnancy, but using this marker to predict such conditions proved challenging.
Objective: To clarify and compare if the neurological outcomes of fetal growth restriction (FGR) cases with abnormal cord insertion (CI) are associated with a higher risk of a poor neurological outcome in subjects aged 3 years or less versus those with normal CI.
Methods: A multicenter retrospective cohort study was conducted among patients with a birth weight lower than the 3rd percentile, based on the standard reference values for Japanese subjects after 22 weeks' gestation, who were treated at a consortium of nine perinatal centers in Japan between June 2005 and March 2011. Patients whose birth weights were less than the 3rd percentile and whose neurological outcomes from birth to 3 years of age could be checked from their medical records were analyzed.
Myelomeningocele (MMC) is a congenital disease without genetic abnormalities. Neurological symptoms are irreversibly impaired after birth, and no effective treatment has been reported to date. Only surgical repairs have been reported so far.
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- - The study focused on a 3-year nationwide project in Japan to implement non-invasive prenatal testing (NIPT) for detecting aneuploidy in high-risk pregnant women, with proper genetic counseling provided.
- - Out of 30,613 tests conducted, only 1.81% were positive for aneuploidy, with high true-positive rates for trisomies, and a very low false-negative rate (0.02%).
- - The research emphasizes the need for a robust genetic counseling system and a supportive welfare framework to assist women who choose to have children with chromosomal conditions.
Article Synopsis
- Human herpesvirus 6B (HHV-6B) is primarily known for causing mild illness in infants, specifically exanthema subitum, but can lead to serious conditions like febrile seizures and encephalitis in some cases.
- Research found elevated levels of interleukin (IL)-1β and basic fibroblast growth factor (bFGF) in the cerebrospinal fluid of patients with HHV-6B-related encephalitis compared to those with other types of febrile seizures.
- Laboratory studies showed that IL-1β and bFGF enhanced the expression of HHV-6B in infected brain cells, suggesting they play a role in promoting HHV-6B growth and the
Aim: The aim of this study was to evaluate the association between oligohydramnios and other perinatal factors in preterm small-for-gestational-age (SGA) infants who had cerebral palsy at 18 months of age or who had died before this age.
Methods: This retrospective study included 320 infants with birthweights < 3rd percentile delivered between 22 and 33 complete weeks of gestation. We evaluated the incidence of CP at 18 months of age and of death before this age.
Prenatal Diagnosis of Isolated Agnathia-Otocephaly: A Case Report and Review of the Literature.
Case Rep Obstet Gynecol
August 2016
Agnathia is a rare disease characterized by the absence of a mandible. Few cases of prenatally diagnosed isolated agnathia have been reported. We present a case report and review of the literature of prenatally diagnosed agnathia.
View Article and Find Full Text PDFObjective: To establish a prenatal prognostic classification of severe small-for-gestational-age (SGA) infants based on gestational age and fetal findings.
Methods: A retrospective cohort study of 366 singleton infants (birth weight <3rd percentile) delivered between 22 and 34 weeks' gestation at nine tertiary perinatal centers. A decision tree model was developed for the prediction of death or severe morbidity.
A pregnant Japanese female was referred to our hospital due to intrauterine fetal growth restriction. A prenatal diagnosis of right pulmonary agenesis could be made using ultrasonography and fetal magnetic resonance imaging, and a Caesarian section was performed at 34 weeks of gestation. The infant developed a respiratory disorder immediately, received systemic management in the neonatal intensive care unit (NICU), and was discharged at age of 103 days without any severe sequelae.
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