Publications by authors named "Tomohiro Tanemoto"

Article Synopsis
  • The study focused on identifying pregnant women at risk for postpartum depression (PDS) using the Edinburgh Postnatal Depression Scale (EPDS) during different trimesters and shortly after giving birth.
  • It involved following 129 healthy pregnant women throughout their pregnancy and evaluating their EPDS scores to determine the best time for screening and the effectiveness of different cutoff scores.
  • Results showed the second trimester screening with a cutoff score of 4/5 had the highest predictive value for PDS, particularly among women with a family history of mental illness.
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  • A study was conducted to understand why some noninvasive prenatal tests (NIPT) yield nonreportable results by looking at maternal characteristics and related details.
  • Out of 34,626 pregnant women tested, 110 (0.32%) had nonreportable cfDNA results, primarily due to low fetal fraction or altered genomic profiles.
  • The research highlights the importance of classifying nonreportable results to offer clearer information and lessen anxiety for expecting mothers.
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  • - The study aimed to evaluate how fetal fractions in non-invasive prenatal testing (NIPT) can help predict pregnancy complications like gestational diabetes and hypertension by comparing results from different gestational ages and maternal characteristics.
  • - Conducted as a multicenter cohort study, it analyzed data from 5,582 women with negative NIPT results to explore the links between fetal fractions and pregnancy outcomes such as miscarriages and complications.
  • - Results indicated that women who developed hypertensive disorders tended to have lower fetal fractions early in pregnancy, but using this marker to predict such conditions proved challenging.
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Objective: To clarify and compare if the neurological outcomes of fetal growth restriction (FGR) cases with abnormal cord insertion (CI) are associated with a higher risk of a poor neurological outcome in subjects aged 3 years or less versus those with normal CI.

Methods: A multicenter retrospective cohort study was conducted among patients with a birth weight lower than the 3rd percentile, based on the standard reference values for Japanese subjects after 22 weeks' gestation, who were treated at a consortium of nine perinatal centers in Japan between June 2005 and March 2011. Patients whose birth weights were less than the 3rd percentile and whose neurological outcomes from birth to 3 years of age could be checked from their medical records were analyzed.

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Myelomeningocele (MMC) is a congenital disease without genetic abnormalities. Neurological symptoms are irreversibly impaired after birth, and no effective treatment has been reported to date. Only surgical repairs have been reported so far.

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  • - The study focused on a 3-year nationwide project in Japan to implement non-invasive prenatal testing (NIPT) for detecting aneuploidy in high-risk pregnant women, with proper genetic counseling provided.
  • - Out of 30,613 tests conducted, only 1.81% were positive for aneuploidy, with high true-positive rates for trisomies, and a very low false-negative rate (0.02%).
  • - The research emphasizes the need for a robust genetic counseling system and a supportive welfare framework to assist women who choose to have children with chromosomal conditions.
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  • Human herpesvirus 6B (HHV-6B) is primarily known for causing mild illness in infants, specifically exanthema subitum, but can lead to serious conditions like febrile seizures and encephalitis in some cases.
  • Research found elevated levels of interleukin (IL)-1β and basic fibroblast growth factor (bFGF) in the cerebrospinal fluid of patients with HHV-6B-related encephalitis compared to those with other types of febrile seizures.
  • Laboratory studies showed that IL-1β and bFGF enhanced the expression of HHV-6B in infected brain cells, suggesting they play a role in promoting HHV-6B growth and the
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Aim: The aim of this study was to evaluate the association between oligohydramnios and other perinatal factors in preterm small-for-gestational-age (SGA) infants who had cerebral palsy at 18 months of age or who had died before this age.

Methods: This retrospective study included 320 infants with birthweights < 3rd percentile delivered between 22 and 33 complete weeks of gestation. We evaluated the incidence of CP at 18 months of age and of death before this age.

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Agnathia is a rare disease characterized by the absence of a mandible. Few cases of prenatally diagnosed isolated agnathia have been reported. We present a case report and review of the literature of prenatally diagnosed agnathia.

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Objective: To establish a prenatal prognostic classification of severe small-for-gestational-age (SGA) infants based on gestational age and fetal findings.

Methods: A retrospective cohort study of 366 singleton infants (birth weight <3rd percentile) delivered between 22 and 34 weeks' gestation at nine tertiary perinatal centers. A decision tree model was developed for the prediction of death or severe morbidity.

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A pregnant Japanese female was referred to our hospital due to intrauterine fetal growth restriction. A prenatal diagnosis of right pulmonary agenesis could be made using ultrasonography and fetal magnetic resonance imaging, and a Caesarian section was performed at 34 weeks of gestation. The infant developed a respiratory disorder immediately, received systemic management in the neonatal intensive care unit (NICU), and was discharged at age of 103 days without any severe sequelae.

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