Quantifying Wind-Driven Firebrand Production from Roofing Assembly Combustion.

Large outdoor fires present a risk to the built environment. Examples often in the international media reports are wildfires that spread into communities, referred to as Wildland-Urban Interface (WUI) fires. Other examples are large urban fires including those that have occurred after earthquakes.

Decrease in rat internal anal pressure with the use of a topical ointment containing a killed E. coli culture suspension.

Objectives: The present study aimed to clarify the mechanisms of a topical ointment containing an Escherichia coli culture suspension and hydrocortisone (Posterisan forte, BCS+HC) in lowering internal anal pressure in conscious rats.

Materials And Methods: Internal anal pressure was measured using a water-filled balloon system for consecutive 10-min periods. The changes in pressure were evaluated by the number of peaks above 20 mmH2O between 1 and 8 min of recording.

Effect of heparinoid on the production of tissue inhibitor of metalloproteinases (TIMP)-3 in rheumatoid synovial fibroblasts.

Heparinoid is one of the major contents of Mobilat widely used as an antirheumatic drug. To clarify the precise mechanisms of the antirheumatic effect of heparinoid, we investigated its effects on the production of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) from rheumatoid synovial fibroblasts stimulated (or not) with interleukin-1 alpha (IL-1alpha) at 100 units mL(-1). The expression of TIMP-3 mRNA was also investigated in a similar manner.