Publications by authors named "Tomohiko Harunari"
Background: The precise details of atrial activation around the triangle of Koch (ToK) remain unknown. We evaluated the relationship between the atrial-activation pattern around the ToK and success sites for slow-pathway (SP) modification ablation in slow-fast atrioventricular reentrant tachycardia (AVNRT).
Methods: Thirty patients with slow-fast AVNRT who underwent successful ablation were enrolled.
Pulmonary vein (PV) reconnection is a major reason for recurrence after catheter ablation of paroxysmal atrial fibrillation (PAF). However, the timing of the recurrence varies between patients, and recurrence >1 year after ablation is not uncommon. We sought to elucidate the characteristics of atrial fibrillation (AF) that recurred in different follow-up periods.
View Article and Find Full Text PDFDE-MDCT Predicts Regional Functional Improvement After Reperfused AMI.
JACC Cardiovasc Imaging
February 2020
Article Synopsis
- The superior vena cava (SVC) is linked to initiating atrial fibrillation (AF) by contributing to electrical disturbances that don't involve pulmonary veins.
- In a study with 47 patients, researchers used electroanatomical mapping to measure the sleeve lengths of pulmonary veins (PVs) and the SVC, discovering that SVC and left superior PV sleeves were longer than others.
- Findings suggest that left-sided PVs have a connection to patients' body surface area, while there’s a correlation between the sleeve lengths of right-sided PVs and the SVC, offering new insights into AF mechanisms.
Article Synopsis
- Renal dysfunction leads to the buildup of uremic toxins like indoxyl sulfate (IS), which increases the risk of atrial fibrillation (AF) due to inflammation and oxidative stress.
- A study involving 125 patients who underwent catheter ablation for AF found that those with higher serum IS levels (≥0.65 μg/mL) had significantly lower rates of staying AF-free after one year compared to those with lower IS levels (60.1% vs. 85.2%).
- The research shows that elevated IS levels at baseline are a strong predictor of AF recurrence after treatment, with a hazard ratio indicating over three times the risk of recurrence for patients with high IS levels.
Background: Ablation of the pulmonary venous carina is occasionally required for pulmonary vein isolation (PVI) despite its nonessential role in ipsilateral PVI from the anatomical (endocardial) viewpoint. Although the Bachmann bundle (BB) is a common and main interatrial band, local variations in small tongues of muscular fibers were frequently found in autopsy studies.
Objective: We sought to clarify the effect of the electrical conduction pattern from the right atrium (RA) to the left atrium (LA) during sinus rhythm on the necessity of performing right-sided pulmonary venous carina ablation to achieve PVI.
Difficulty and potential risks of single-lead atrioventricular synchronous pacing leads in transvenous lead extraction.
Interact Cardiovasc Thorac Surg
December 2018
Article Synopsis
- The study aimed to identify factors impacting the success of lead extraction using an excimer laser sheath, a process typically required for patients with implanted cardiac leads.
- A total of 372 leads from 176 patients were analyzed, revealing a high success rate of 96%, with complications linked to the lead type and duration since implantation.
- Key findings indicated that the use of a VDD-pacing lead significantly increased chances of procedural failure, highlighting the need for operators to be cautious when extracting these specific leads.
Background: The association of Mehran risk score (MRS) with long-term prognosis in patients treated with percutaneous coronary intervention (PCI) has not been fully reported. We investigated the association between MRS and clinical outcomes in patients who underwent PCI.
Methods: Study subjects comprised 2198 patients treated with PCI from the Ibaraki Cardiovascular Assessment Study multicenter registry, excluding patients receiving hemodialysis or who died within 7 days.
Article Synopsis
- - This study compared the coagulation status of 85 Japanese patients with non-valvular atrial fibrillation (NVAF) being treated with rivaroxaban versus warfarin, two anticoagulants used to prevent blood clots.
- - Results showed that while prothrombin time (PT) levels were similar between the two groups, the prothrombin fragment 1+2 (F1+2) levels were significantly higher in the rivaroxaban group, indicating greater thrombin generation.
- - The research indicated that rivaroxaban maintains stable thrombin generation levels over time, whereas warfarin may more effectively suppress thrombin production.
Article Synopsis
- * Out of 2,198 CAD patients analyzed, those who had statin pretreatment had a significantly lower incidence of CI-AKI compared to those who did not (3.5% vs. 10.6%).
- * The results indicated that statin pretreatment is a strong predictor of reduced risk for CI-AKI, suggesting potential benefits for CAD patients undergoing PCI.
Background: To evaluate the incidence and clinical predictors of contrast-induced acute kidney injury (CI-AKI) in patients with ST-segment elevation myocardial infarction (STEMI), unstable angina pectoris/non-STEMI (UAP/NSTEMI), and stable AP (SAP) undergoing percutaneous coronary intervention (PCI).
Methods And Results: We enrolled 1,954 patients (SAP, n=1,222; UAP/NSTEMI, n=277; STEMI, n=455) who underwent PCI. Patients were categorized according to contrast media volume/estimated glomerular filtration rate ratio (CV/eGFR low: <2.